Minocycline hydrochloride and Valacyclovir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Minocycline hydrochloride (minocycline hydrochloride) and Valacyclovir (valacyclovir hydrochloride). Common drug interactions include hospitalisation among females and pancytopenia among males.

The phase IV clinical study analyzes what interactions people have when they take Minocycline hydrochloride and Valacyclovir. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Minocycline hydrochloride?

Minocycline hydrochloride has active ingredients of minocycline hydrochloride. It is often used in acne. eHealthMe is studying from 5,255 Minocycline hydrochloride users. Check the latest studies of Minocycline hydrochloride.

What is Valacyclovir?

Valacyclovir has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes. eHealthMe is studying from 42,107 Valacyclovir users. Check the latest studies of Valacyclovir.

On Jul, 21, 2026

23 people who take Minocycline hydrochloride and Valacyclovir together, and have interactions are studied.

Minocycline hydrochloride and Valacyclovir drug interactions.

What are the common drug interactions of Minocycline Hydrochloride and Valacyclovir, by gender? *:

female:

Hospitalisation
Sinusitis (inflammation of sinus)
Abdominal pain
Hepatic vein thrombosis (obstruction in the veins of the liver caused by a blood clot)
Hunger
Limb injury
Muscle rupture (tear in muscle)
Nocturia (the need to get up in the night to urinate)
Oral herpes (viral infection of mouth)
Peripheral coldness

male:

Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Cellulitis (infection under the skin)
Enteritis infectious (infection with feline parvovirus (fpv), also known as feline panleucopenia virus)
Febrile neutropenia (fever with reduced white blood cells)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Haemoglobin decreased
Hyperplasia (enlargement of an organ or tissue)
Ileus (a painful obstruction of the ileum or other part of the intestine)
White blood cell count decreased

What are the common drug interactions of Minocycline Hydrochloride and Valacyclovir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Brain abscess
Cystitis haemorrhagic (blood in the urine and painful voiding)
Dyspnoea (difficult or laboured respiration)
Fluid retention (an abnormal accumulation of fluid in the blood)
Infection
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pneumonia
Respiratory failure (inadequate gas exchange by the respiratory system)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Arthritis infective (purulent invasion of a joint by an infectious agent which produces arthritis)

20-29:

Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Erythema (redness of the skin)
Erythema multiforme (a type of hypersensitivity reaction)
Lichenification (thickening and hardening of the skin)
Lung transplant
Pain in extremity
Pyrexia (fever)
Scab (a hard coating on the skin formed during the wound healing)
Skin erosion (a discontinuity of the skin)

30-39:

Confusional state
Suicide attempt
Vitamin d decreased

40-49:

Sinusitis (inflammation of sinus)
Abdominal pain
Hepatic vein thrombosis (obstruction in the veins of the liver caused by a blood clot)
Hospitalisation
Hunger
Limb injury
Muscle rupture (tear in muscle)
Nocturia (the need to get up in the night to urinate)
Oral herpes (viral infection of mouth)
Peripheral coldness

50-59:

Melanosis (a disorder of pigmentation of the wall of the colon)

60+:

Abscess (pus)
Arthralgia (joint pain)
Bladder disorder
Eye infection
Eye pain
Intraocular pressure increased
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Peripheral swelling

What are the existing conditions these people have? *

Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 34.78%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 34.78%
Drowsiness: 6 people, 26.09%
Pain: 5 people, 21.74%
Sedation: 3 people, 13.04%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 3 people, 13.04%
Bacterial Infection: 3 people, 13.04%
Constipation: 3 people, 13.04%
Cytomegalovirus Infection: 3 people, 13.04%
Depression: 3 people, 13.04%

* Approximation only. Some reports may have incomplete information.

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