Mint and Vitamin d3 drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mint (peppermint) and Vitamin d3 (cholecalciferol). Common drug interactions include insomnia among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Mint and Vitamin d3. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Mint?

Mint has active ingredients of peppermint. eHealthMe is studying from 1,344 Mint users. Check the latest studies of Mint.

What is Vitamin d3?

Vitamin d3 has active ingredients of cholecalciferol. It is often used in heart health. eHealthMe is studying from 32,172 Vitamin d3 users. Check the latest studies of Vitamin d3.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

16 people who take Mint and Vitamin d3 together, and have interactions are studied.

What are the common drug interactions of Mint and Vitamin D3, by gender? *:

female:

Insomnia (sleeplessness)
Injection site pain
Diarrhoea
Irritable bowel syndrome
Malaise (a feeling of general discomfort or uneasiness)
Pain
Rash
Constipation
Hypertension (high blood pressure)
Oedema peripheral (superficial swelling)

male:

Diarrhoea
Agitation (state of anxiety or nervous excitement)
Palpitations (feelings or sensations that your heart is pounding or racing)
Sneezing
Stomatitis (inflammation of mucous membrane of mouth)
Tachyphrenia (abnormally rapid mental activity)
Thrombocytopenia (decrease of platelets in blood)
Anxiety
Energy increased
Feeling hot

What are the common drug interactions of Mint and Vitamin D3, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Insomnia (sleeplessness)
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Blood sodium increased
Constipation
Dry eye (lack of adequate tears)
Hemiplegic migraine (migraine attacks occurring in two or more people in the same family who experience weakness on one side of body)
Hypertension (high blood pressure)
Irritable bowel syndrome
Lymphocytic hypophysitis (inflammation of the pituitary gland)
Migraine (headache)

40-49:

Injection site pain
Diarrhoea
Abdominal pain
Abdominal rigidity
Back pain
Depression
Dizziness
Drug ineffective
Fatigue (feeling of tiredness)
Gastrointestinal disorder (functional problems of gastrointestinal tract)

50-59:

Insomnia (sleeplessness)
Oedema peripheral (superficial swelling)
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)

60+:

Stomatitis (inflammation of mucous membrane of mouth)
Anxiety
Diarrhoea
Insomnia (sleeplessness)
Menstrual disorder (disease of menstrual cycle)
Mucosal inflammation (infection of mucous membrane)
Neutropenia (an abnormally low number of neutrophils)
Night sweats (sweating in night)
Thrombocytopenia (decrease of platelets in blood)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 31.25%
Headache (pain in head): 5 people, 31.25%
Hypersensitivity: 5 people, 31.25%
Ankylosing Spondylitis (type of arthritis affecting the spine): 4 people, 25.00%
Bipolar Disorder (mood disorder): 3 people, 18.75%
Pain: 2 people, 12.50%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 12.50%
Sinusitis (inflammation of sinus): 2 people, 12.50%
Psychotic Disorder: 2 people, 12.50%
Migraine (headache): 2 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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