Miralax and Odefsey drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Miralax (polyethylene glycol 3350) and Odefsey (emtricitabine; rilpivirine hydrochloride; tenofovir alafenamide fumarate). Common drug interactions include emotional distress among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Miralax and Odefsey. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Miralax?

Miralax has active ingredients of polyethylene glycol 3350. It is often used in constipation. eHealthMe is studying from 81,754 Miralax users. Check the latest studies of Miralax.

What is Odefsey?

Odefsey has active ingredients of emtricitabine; rilpivirine hydrochloride; tenofovir alafenamide fumarate. It is often used in hiv infection. eHealthMe is studying from 4,605 Odefsey users. Check the latest studies of Odefsey.



On Jul, 23, 2026

14 people who take Miralax and Odefsey together, and have interactions are studied.

Miralax and Odefsey drug interactions.

What are the common drug interactions of Miralax and Odefsey, by gender? *:

female:

  1. Emotional distress
  2. Pain
  3. Chronic kidney disease
  4. Renal failure (kidney dysfunction)
  5. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  6. Anxiety
  7. Bone density decreased
  8. Bone loss
  9. Multiple fractures
  10. Osteoarthritis (a joint disease caused by cartilage loss in a joint)

male:

  1. Anxiety
  2. Pain
  3. Abnormal dreams
  4. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  5. Cataract (clouding of the lens inside the eye)
  6. Depression
  7. Disturbance in attention
  8. Dizziness
  9. Dysphemia (stammering or stuttering)
  10. Executive dysfunction

What are the common drug interactions of Miralax and Odefsey, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Chronic kidney disease
  2. Emotional distress
  3. Pain
  4. Renal failure (kidney dysfunction)

30-39:

n/a

40-49:

  1. Anxiety
  2. Bone density decreased
  3. Osteoporosis (bones weak and more likely to break)
  4. Pain
  5. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  6. Emotional distress
  7. Osteopenia (a condition where bone mineral density is lower than normal)
  8. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  9. Chronic kidney disease
  10. Hip arthroplasty

50-59:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Chronic kidney disease
  4. Emotional distress
  5. Pain
  6. Abdominal pain
  7. Back pain
  8. Bedridden
  9. Decreased activity
  10. Depression

60+:

  1. Abnormal dreams
  2. Cataract (clouding of the lens inside the eye)
  3. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  4. Muscular weakness (muscle weakness)
  5. Nausea (feeling of having an urge to vomit)
  6. Visual impairment
  7. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  8. Anxiety
  9. Confusional state
  10. Disturbance in attention

What are the existing conditions these people have? *

  1. Pain: 6 people, 42.86%
  2. Bacterial Infection: 5 people, 35.71%
  3. High Blood Pressure: 4 people, 28.57%
  4. Inflammation: 3 people, 21.43%
  5. Prostate Cancer: 3 people, 21.43%
  6. Depression: 3 people, 21.43%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 21.43%
  8. Amenorrhea (absence of a menstrual period in a woman of reproductive age): 3 people, 21.43%
  9. Muscle Spasms (muscle contraction): 3 people, 21.43%
  10. Nausea (feeling of having an urge to vomit): 3 people, 21.43%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Miralax and Odefsey:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Miralax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Odefsey:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Miralax and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Odefsey and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on polyethylene glycol 3350 and emtricitabine; rilpivirine hydrochloride; tenofovir alafenamide fumarate (the active ingredients of Miralax and Odefsey, respectively), and Miralax and Odefsey (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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