Mirapex and Hydrocodone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mirapex (pramipexole dihydrochloride) and Hydrocodone (hydrocodone bitartrate; ibuprofen). Common drug interactions include tubulointerstitial nephritis among females and abnormal behaviour among males.

The phase IV clinical study analyzes what interactions people have when they take Mirapex and Hydrocodone. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Mirapex?

Mirapex has active ingredients of pramipexole dihydrochloride. It is often used in restless leg syndrome. eHealthMe is studying from 20,622 Mirapex users. Check the latest studies of Mirapex.

What is Hydrocodone?

Hydrocodone has active ingredients of hydrocodone bitartrate; ibuprofen. eHealthMe is studying from 13,115 Hydrocodone users. Check the latest studies of Hydrocodone.

On Aug, 03, 2026

50 people who take Mirapex and Hydrocodone together, and have interactions are studied.

Mirapex and Hydrocodone drug interactions.

What are the common drug interactions of Mirapex and Hydrocodone, by gender? *:

female:

Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
White blood cell count increased
Abdominal pain
Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
Arthropathy
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Biliary tract disorder
Blood glucose increased
Body height decreased

male:

Abnormal behaviour
Depression
Cerebral artery thrombosis (clot formation in brain blood vessels)
Chronic kidney disease
Coma (state of unconsciousness lasting more than six hours)
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Diffuse large b-cell lymphoma (cancer of b cells, a type of white blood cell)
Drug toxicity
Dyspnoea (difficult or laboured respiration)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)

What are the common drug interactions of Mirapex and Hydrocodone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abdominal pain
Anaemia (lack of blood)
Biliary tract disorder
Mean cell volume decreased (less of the average red blood cell volume)
Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
Meralgia paraesthetica (a neurological (nerve) condition that causes pain in the outer thigh)
Neurogenic bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion)

50-59:

Pain
Chronic kidney disease
Drug ineffective
Renal failure (kidney dysfunction)
Alopecia (absence of hair from areas of the body)
Fatigue (feeling of tiredness)
Infection
Renal tubular necrosis (death of kidney tubules)
Urinary tract infection
Dyspepsia (indigestion)

60+:

Pain
Visual impairment
Renal failure (kidney dysfunction)
Acute respiratory distress syndrome
Anaemia (lack of blood)
Asthenia (weakness)
Bedridden
Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
Cardiac arrest
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

What are the existing conditions these people have? *

Pain: 12 people, 24.00%
Immunodeficiency Common Variable: 9 people, 18.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 12.00%
Parkinson's Disease: 6 people, 12.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 10.00%
Depression: 5 people, 10.00%
Stress And Anxiety: 4 people, 8.00%
High Blood Cholesterol: 4 people, 8.00%
Back Pain: 3 people, 6.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 6.00%

* Approximation only. Some reports may have incomplete information.

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