Mirapex and Rapamune drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mirapex (pramipexole dihydrochloride) and Rapamune (sirolimus). Common drug interactions include pneumonia among females and hypertension among males.

The phase IV clinical study analyzes what interactions people have when they take Mirapex and Rapamune. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Mirapex?

Mirapex has active ingredients of pramipexole dihydrochloride. It is often used in restless leg syndrome. eHealthMe is studying from 20,622 Mirapex users. Check the latest studies of Mirapex.

What is Rapamune?

Rapamune has active ingredients of sirolimus. It is often used in kidney transplant. eHealthMe is studying from 13,848 Rapamune users. Check the latest studies of Rapamune.



On Jul, 16, 2026

12 people who take Mirapex and Rapamune together, and have interactions are studied.

Mirapex and Rapamune drug interactions.

What are the common drug interactions of Mirapex and Rapamune, by gender? *:

female:

  1. Pneumonia
  2. Haematochezia (passage of stools containing blood)
  3. Haematocrit decreased
  4. Lymphadenopathy (disease or enlargement of lymph nodes)
  5. Lymphoproliferative disorder (a medical condition in which the immune system makes too many white blood cells)
  6. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  7. Nausea (feeling of having an urge to vomit)
  8. Pyrexia (fever)
  9. Screaming (a long loud piercing cry)
  10. Sinusitis (inflammation of sinus)

male:

  1. Hypertension (high blood pressure)

What are the common drug interactions of Mirapex and Rapamune, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Pneumonia
  2. Vomiting
  3. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  4. Pericardial effusion (fluid around the heart)
  5. Pleural effusion (water on the lungs)
  6. Aphthous stomatitis (mouth ulcer)
  7. Diarrhoea
  8. Disease recurrence
  9. Gastric ulcer (stomach ulcer)
  10. Haematochezia (passage of stools containing blood)

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Hypertension (high blood pressure)

50-59:

  1. Diarrhoea
  2. Nausea (feeling of having an urge to vomit)
  3. Vomiting

60+:

  1. Acute myocardial infarction (acute heart attack)
  2. Anoxic encephalopathy (brain damage due to lack of oxygen)
  3. Pulmonary oedema (fluid accumulation in the lungs)
  4. Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
  5. Brain injury
  6. Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
  7. Cardiac arrest
  8. Cardiac failure
  9. Cerebral calcification (abnormal deposits of calcium in certain areas of the brain)
  10. Chest pain

What are the existing conditions these people have? *

  1. High Blood Pressure: 3 people, 25.00%
  2. Quit Smoking: 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Mirapex and Rapamune?

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- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Mirapex and Rapamune:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Mirapex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Rapamune:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mirapex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Rapamune and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on pramipexole dihydrochloride and sirolimus (the active ingredients of Mirapex and Rapamune, respectively), and Mirapex and Rapamune (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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