Opdivo and Glaucoma - a phase IV clinical study of FDA data

Summary:

Glaucoma is reported as a side effect among people who take Opdivo (nivolumab), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Yervoy, and have Gastric cancer.

The phase IV clinical study analyzes which people have Glaucoma when taking Opdivo. It is created by eHealthMe based on reports of 56,294 people who have side effects when taking Opdivo from the FDA, and is updated regularly.

What is Opdivo?

Opdivo has active ingredients of nivolumab. eHealthMe is studying from 56,331 Opdivo users. Check the latest studies of Opdivo.

What is Glaucoma?

Glaucoma (increased fluid pressure in the eye with vision loss) is found to be associated with 1,236 drugs and 1,655 conditions by eHealthMe. Check the latest studies of Glaucoma.



On Jul, 16, 2026

56,294 people reported to have side effects when taking Opdivo.
Among them, 22 people (0.04%) have Glaucoma.

Could Opdivo cause Glaucoma?

Among these 22 people:

How long have people been on Opdivo when they have Glaucoma? *

  • < 1 month: 42.86 %
  • 1 - 6 months: 42.86 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 14.29 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Glaucoma when taking Opdivo? *

  • female: 0.0 %
  • male: 100 %

What is the age of people who have Glaucoma when taking Opdivo? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 12.5 %
  • 50-59: 12.5 %
  • 60+: 75.0 %

What are other drugs people take besides Opdivo? *

  1. Yervoy: 6 people, 27.27%
  2. Oxaliplatin: 4 people, 18.18%
  3. Amlodipine: 3 people, 13.64%
  4. Zyprexa: 2 people, 9.09%
  5. Cyramza: 2 people, 9.09%
  6. Decadron: 2 people, 9.09%
  7. Emend: 2 people, 9.09%
  8. Fluorouracil: 2 people, 9.09%
  9. Levoleucovorin Calcium: 2 people, 9.09%
  10. Aloxi: 2 people, 9.09%

What are other side effects people have besides Glaucoma? *

  1. Cataract (clouding of the lens inside the eye): 6 people, 27.27%
  2. Uveitis (inflammation of the uvea): 3 people, 13.64%
  3. Abdominal Pain: 2 people, 9.09%
  4. Nausea (feeling of having an urge to vomit): 2 people, 9.09%
  5. Dyschezia (difficulty in defecating): 2 people, 9.09%
  6. Fatigue (feeling of tiredness): 2 people, 9.09%
  7. Constipation: 2 people, 9.09%
  8. Conjunctival Haemorrhage (bleeding underneath the conjunctiva): 2 people, 9.09%
  9. Weight Increased: 2 people, 9.09%
  10. Chapped Lips (cracking, fissuring, and peeling of the skin f lip): 2 people, 9.09%

What are the existing conditions these people have? *

  1. Gastric Cancer (stomach cancer): 5 people, 22.73%
  2. Oesophageal Carcinoma (cancer tumour of oesophagus): 2 people, 9.09%
  3. Non-Small Cell Lung Cancer Recurrent (type of epithelial lung cancer reoccurrence): 2 people, 9.09%
  4. Malignant Melanoma (skin cancer rises from melancytes): 2 people, 9.09%
  5. Cachexia (loss of weight): 2 people, 9.09%
  6. Renal Cell Carcinoma (a kidney cancer): 1 person, 4.55%
  7. Neoplasm Malignant (cancer tumour): 1 person, 4.55%
  8. Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 1 person, 4.55%
  9. Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 1 person, 4.55%
  10. Malignant Melanoma Stage Iv (the cancer has spread to other places in the body, such as the lung, liver, brain, bone, soft tissue, or gastrointestinal (gi) tract. cancer may have spread to places in the skin far away from where it first started): 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Opdivo and have Glaucoma?

- Check whether Glaucoma is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Opdivo:

Glaucoma treatments and more:

How severe was Glaucoma and when was it recovered:

Expand to all the drugs that have ingredients of nivolumab:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Opdivo:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Glaucoma:

Browse all the conditions that are associated with Glaucoma:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on nivolumab (the active ingredients of Opdivo) and Opdivo (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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