Pletal and Darvocet drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pletal (cilostazol) and Darvocet (acetaminophen; propoxyphene hydrochloride). Common drug interactions include colour blindness acquired among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Pletal and Darvocet. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Pletal?

Pletal has active ingredients of cilostazol. It is often used in blockage of leg arteries. eHealthMe is studying from 6,341 Pletal users. Check the latest studies of Pletal.

What is Darvocet?

Darvocet has active ingredients of acetaminophen; propoxyphene hydrochloride. It is often used in pain. eHealthMe is studying from 12,131 Darvocet users. Check the latest studies of Darvocet.

On Jul, 16, 2026

28 people who take Pletal and Darvocet together, and have interactions are studied.

What are the common drug interactions of Pletal and Darvocet, by gender? *:

female:

Colour blindness acquired (development of colour vision disability due to damage to eye)
Dry eye (lack of adequate tears)
Dystonia (abnormal muscle tone)
Ear disorder
External ear pain
Flat anterior chamber of eye
Hypertension (high blood pressure)
Iris cyst (cyst in eye)
Leukoplakia oral (white and gray patches inside the mouth)
Mastication disorder (disease of chewing food)

male:

Cardiac failure congestive
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Cardiac arrest
Chronic kidney disease
Death
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hypotension (abnormally low blood pressure)
Lobar pneumonia (a form of pneumonia that affects a large and continuous area of the lobe of a lung)
Pleural effusion (water on the lungs)
Pulmonary oedema (fluid accumulation in the lungs)

What are the common drug interactions of Pletal and Darvocet, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Carotid artery disease
Chronic kidney disease
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Renal disorder (kidney disease)

60+:

Dysphagia (a condition in which swallowing is difficult or painful)
Tardive dyskinesia (a disorder that involves involuntary movements)
Balance disorder
Blindness
Dizziness
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Neck pain
Nervous system disorder (a general class of medical conditions affecting the nervous system)
Postnasal drip
Spinal osteoarthritis (joint cartilage loss in spine)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 20 people, 71.43%
Sleep Disorder: 5 people, 17.86%
High Blood Cholesterol: 5 people, 17.86%
Diarrhea: 5 people, 17.86%
Diabetes: 5 people, 17.86%
Blood Phosphorus Decreased: 5 people, 17.86%
Arterial Disorder: 5 people, 17.86%
Angiopathy (generic term for a disease of the blood vessels): 5 people, 17.86%
Joint Pain: 2 people, 7.14%
High Blood Pressure: 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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