1. Home
  2. Analysis
  3. Fluphenazine
  4. Hyponatremia

Fluphenazine and Hyponatremia - a phase IV clinical study of FDA data

Summary:

Hyponatremia is reported as a side effect among people who take Fluphenazine (fluphenazine decanoate), especially for people who are male, 40-49 old, also take Isoptin, and have Depression.

The phase IV clinical study analyzes which people have Hyponatremia when taking Fluphenazine. It is created by eHealthMe based on reports of 2,335 people who have side effects when taking Fluphenazine from the FDA, and is updated regularly.

What is Fluphenazine?

Fluphenazine has active ingredients of fluphenazine decanoate. It is often used in schizophrenia. eHealthMe is studying from 2,364 Fluphenazine users. Check the latest studies of Fluphenazine.

What is Hyponatremia?

Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration) is found to be associated with 1,939 drugs and 2,272 conditions by eHealthMe. Check the latest studies of Hyponatremia.

On Jul, 16, 2026

2,335 people reported to have side effects when taking Fluphenazine.
Among them, 66 people (2.83%) have Hyponatremia.

Could Fluphenazine cause Hyponatremia?

Among these 66 people:

What is the gender of people who have Hyponatremia when taking Fluphenazine? *

  • female: 25 %
  • male: 75 %

What is the age of people who have Hyponatremia when taking Fluphenazine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 24.19 %
  • 40-49: 37.1 %
  • 50-59: 19.35 %
  • 60+: 19.35 %

What are other drugs people take besides Fluphenazine? *

  1. Allopurinol: 8 people, 12.12%
  2. Olanzapine: 8 people, 12.12%
  3. Cisplatin: 8 people, 12.12%
  4. Isoptin: 8 people, 12.12%
  5. Haloperidol: 7 people, 10.61%
  6. Diazepam: 6 people, 9.09%
  7. Hydrochlorothiazide: 6 people, 9.09%
  8. Alprazolam: 6 people, 9.09%
  9. Zolpidem: 6 people, 9.09%
  10. Vitamin B12: 5 people, 7.58%

What are other side effects people have besides Hyponatremia? *

  1. Inappropriate Antidiuretic Hormone Secretion: 36 people, 54.55%
  2. Loss Of Consciousness: 23 people, 34.85%
  3. Confusion: 23 people, 34.85%
  4. Consciousness - Decreased: 17 people, 25.76%
  5. Hypokalemia (low potassium): 16 people, 24.24%
  6. Pancreatitis Haemorrhagic (inflammation of pancreas with bleeding): 15 people, 22.73%
  7. Hyperglycemia (high blood sugar): 15 people, 22.73%
  8. Dizziness: 14 people, 21.21%
  9. Urination - Excessive Volume: 13 people, 19.70%
  10. Brain Oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain): 13 people, 19.70%

What are the existing conditions these people have? *

  1. Depression: 13 people, 19.70%
  2. Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 8 people, 12.12%
  3. Stress And Anxiety: 6 people, 9.09%
  4. Insomnia (sleeplessness): 6 people, 9.09%
  5. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 5 people, 7.58%
  6. Cardiac Disorder: 4 people, 6.06%
  7. Spindle Cell Sarcoma (a type of connective tissue cancer in which the cells): 3 people, 4.55%
  8. Hypertensive Cardiomyopathy (heart disease caused by high blood pressure): 3 people, 4.55%
  9. High Blood Pressure: 3 people, 4.55%
  10. Psychotic Disorder: 2 people, 3.03%

* Approximation only. Some reports may have incomplete information.

Do you take Fluphenazine and have Hyponatremia?

- Check whether Hyponatremia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fluphenazine:

Hyponatremia treatments and more:

How severe was Hyponatremia and when was it recovered:

Expand to all the drugs that have ingredients of fluphenazine decanoate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Fluphenazine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyponatremia:

Browse all the conditions that are associated with Hyponatremia:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on fluphenazine decanoate (the active ingredients of Fluphenazine) and Fluphenazine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe:

© 2026 eHealthMe.com. All rights reserved. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy.