Mirena and Gilenya drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mirena (levonorgestrel) and Gilenya (fingolimod). Common drug interactions include muscular weakness among females and foetal arrhythmia among males.

The phase IV clinical study analyzes what interactions people have when they take Mirena and Gilenya. It is created by eHealthMe based on reports of 97 people who take the same drugs from the FDA, and is updated regularly.

What is Mirena?

Mirena has active ingredients of levonorgestrel. It is often used in birth control. eHealthMe is studying from 145,266 Mirena users. Check the latest studies of Mirena.

What is Gilenya?

Gilenya has active ingredients of fingolimod. It is often used in multiple sclerosis. eHealthMe is studying from 111,893 Gilenya users. Check the latest studies of Gilenya.

On Jul, 05, 2026

97 people who take Mirena and Gilenya together, and have interactions are studied.

What are the common drug interactions of Mirena and Gilenya, by gender? *:

female:

Muscular weakness (muscle weakness)
Device dislocation
Hypoaesthesia (reduced sense of touch or sensation)
Abdominal pain
Malaise (a feeling of general discomfort or uneasiness)
Dyspnoea (difficult or laboured respiration)
Eye disorder
Ocular hyperaemia (an abnormally large amount of blood in eye)
Palpitations (feelings or sensations that your heart is pounding or racing)
Panic attack

male:

Foetal arrhythmia (abnormal rate or rhythm of the foetus heartbeat)
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)

What are the common drug interactions of Mirena and Gilenya, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Fatigue (feeling of tiredness)
Dizziness
Oropharyngeal pain
Renal cancer (cancer of kidney)
Abdominal pain
Clostridium test positive
Nasopharyngitis (inflammation of the nasopharynx)
Nausea (feeling of having an urge to vomit)
Asthenia (weakness)
Back pain

30-39:

Urinary tract infection
Hypotension (abnormally low blood pressure)
Anion gap increased
Basophil count decreased
Blood alkaline phosphatase increased
Blood calcium increased
Blood creatinine increased
Blood glucose increased
Blood immunoglobulin g increased
Carbon dioxide decreased

40-49:

Procedural pain
Psychomotor hyperactivity (feelings of extreme restlessness)
Red blood cell count decreased
Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
Tinea pedis (a contagious skin infection caused by the ringworm fungus)
Uterine pain
Vaginal haemorrhage (vaginal bleeding)
Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
Visual impairment
Weight decreased

50-59:

Headache (pain in head)
Alopecia (absence of hair from areas of the body)
Nausea (feeling of having an urge to vomit)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
White blood cell count decreased
Breast fibroma (fibroadenomas of the breast are small, solid, rubbery, noncancerous, harmless lumps composed of fibrous and glandular tissue)
Partial seizures (seizures which affect only a part of the brain at onset)
Device dislocation
Gait disturbance
Implant site extravasation

60+:

n/a

What are the existing conditions these people have? *

Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 12 people, 12.37%
Depression: 10 people, 10.31%
Pain: 9 people, 9.28%
Migraine (headache): 8 people, 8.25%
Stress And Anxiety: 6 people, 6.19%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 6 people, 6.19%
Fatigue (feeling of tiredness): 6 people, 6.19%
Suicidal Ideation: 5 people, 5.15%
Seasonal Allergy (allergic condition due to certain season): 5 people, 5.15%
Rickets (softening of bones): 5 people, 5.15%

* Approximation only. Some reports may have incomplete information.

Do you take Mirena and Gilenya?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously