Mitoxantrone hydrochloride and Posaconazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mitoxantrone hydrochloride (mitoxantrone hydrochloride) and Posaconazole (posaconazole). Common drug interactions include bone neoplasm among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Mitoxantrone hydrochloride and Posaconazole. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Mitoxantrone hydrochloride?

Mitoxantrone hydrochloride has active ingredients of mitoxantrone hydrochloride. eHealthMe is studying from 1,060 Mitoxantrone hydrochloride users. Check the latest studies of Mitoxantrone hydrochloride.

What is Posaconazole?

Posaconazole has active ingredients of posaconazole. eHealthMe is studying from 9,475 Posaconazole users. Check the latest studies of Posaconazole.



On Jul, 07, 2026

38 people who take Mitoxantrone hydrochloride and Posaconazole together, and have interactions are studied.

Mitoxantrone hydrochloride and Posaconazole drug interactions.

What are the common drug interactions of Mitoxantrone Hydrochloride and Posaconazole, by gender? *:

female:

  1. Bone neoplasm (tumour of bone)
  2. Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
  3. Device related infection
  4. Disease progression
  5. Drug ineffective
  6. Graft versus host disease in lung (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the lung)
  7. Stenotrophomonas infection
  8. Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
  9. Escherichia sepsis (bacterial infection by escherichia coli)
  10. Mucormycosis (a rare infection caused by organisms that belong to a group of fungi called mucoromycotina)

male:

  1. Drug ineffective
  2. Drug resistance (reduction in effectiveness of a drug)
  3. Encephalitis (inflammation of the brain)
  4. Fungaemia (fungi circulate in the blood)
  5. Hydrocephalus (water on the brain)
  6. Hypokalaemia (low potassium)
  7. Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
  8. Lipase increased
  9. Respiratory failure (inadequate gas exchange by the respiratory system)
  10. Dry skin

What are the common drug interactions of Mitoxantrone Hydrochloride and Posaconazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Cerebral hypoperfusion (a condition in which the brain doesn't get enough blood)
  2. Encephalitis (inflammation of the brain)
  3. Hydrocephalus (water on the brain)
  4. Hypokalaemia (low potassium)
  5. Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
  6. Lipase increased
  7. Respiratory failure (inadequate gas exchange by the respiratory system)

10-19:

  1. Rash maculo-papular (red area on the skin that is covered with small confluent bumps)

20-29:

n/a

30-39:

  1. Bone neoplasm (tumour of bone)
  2. Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
  3. Device related infection
  4. Disease progression
  5. Drug ineffective
  6. Graft versus host disease in lung (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the lung)
  7. Stenotrophomonas infection

40-49:

n/a

50-59:

  1. Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
  2. Escherichia sepsis (bacterial infection by escherichia coli)
  3. Mucormycosis (a rare infection caused by organisms that belong to a group of fungi called mucoromycotina)
  4. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

60+:

  1. Drug ineffective
  2. Drug resistance (reduction in effectiveness of a drug)
  3. Dry skin
  4. Erythema (redness of the skin)
  5. Eye swelling
  6. Face oedema (swelling of face)
  7. Inflammatory marker increased
  8. Localised infection (infection at the single location)
  9. Photosensitivity reaction
  10. Rash

What are the existing conditions these people have? *

  1. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 28 people, 73.68%
  2. Bone Marrow Conditioning Regimen: 16 people, 42.11%
  3. Obliterative Bronchiolitis (bronchiolar inflammation): 5 people, 13.16%
  4. Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 5 people, 13.16%
  5. Pain: 4 people, 10.53%
  6. Nausea And Vomiting: 3 people, 7.89%
  7. Skin Blushing/flushing (a sudden reddening of the face, neck): 2 people, 5.26%
  8. Psychotic Disorder: 2 people, 5.26%
  9. Nausea (feeling of having an urge to vomit): 2 people, 5.26%
  10. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Mitoxantrone hydrochloride and Posaconazole?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Mitoxantrone hydrochloride and Posaconazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Mitoxantrone hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Posaconazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mitoxantrone hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Posaconazole and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on mitoxantrone hydrochloride and posaconazole (the active ingredients of Mitoxantrone hydrochloride and Posaconazole, respectively), and Mitoxantrone hydrochloride and Posaconazole (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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