Mitoxantrone and Metformin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mitoxantrone (mitoxantrone hydrochloride) and Metformin (metformin hydrochloride). Common drug interactions include hair colour changes among females and bronchitis among males.

The phase IV clinical study analyzes what interactions people have when they take Mitoxantrone and Metformin. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Mitoxantrone?

Mitoxantrone has active ingredients of mitoxantrone hydrochloride. eHealthMe is studying from 8,125 Mitoxantrone users. Check the latest studies of Mitoxantrone.

What is Metformin?

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 465,354 Metformin users. Check the latest studies of Metformin.

On Jul, 16, 2026

32 people who take Mitoxantrone and Metformin together, and have interactions are studied.

Mitoxantrone and Metformin drug interactions.

What are the common drug interactions of Mitoxantrone and Metformin, by gender? *:

female:

Hair colour changes
Hair disorder
Headache (pain in head)
Hypokalaemia (low potassium)
Cancer pain
Renal failure (kidney dysfunction)
Tumour flare (temporary increase in symptoms from a cancer after starting treatment)
Activities of daily living impaired
Anaemia (lack of blood)
Anxiety

male:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Metastases to bone (cancer spreads to bone)
Breast mass
Cardiac failure congestive
Carotid artery disease
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Cataract (clouding of the lens inside the eye)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Deafness neurosensory
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

What are the common drug interactions of Mitoxantrone and Metformin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Acute respiratory distress syndrome
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Second primary malignancy (after getting cure a cancer, a new cancer development)

20-29:

n/a

30-39:

Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Hepatic failure (liver failure)
Multi-organ failure (multisystem organ failure)
Multiple drug overdose
Nervous system disorder (a general class of medical conditions affecting the nervous system)
Renal failure (kidney dysfunction)
Respiratory failure (inadequate gas exchange by the respiratory system)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)

40-49:

Alopecia (absence of hair from areas of the body)
Anxiety
Depression
Hair colour changes
Hair disorder

50-59:

Activities of daily living impaired
Back pain
Chest pain
Disease progression
Hepatic mass
Malignant neoplasm progression (cancer tumour came back)
Metastases to bone (cancer spreads to bone)
Metastases to liver (cancer spreads to liver)
Oesophageal carcinoma (cancer tumour of oesophagus)
Cancer pain

60+:

Hypokalaemia (low potassium)
Hypotension (abnormally low blood pressure)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac failure congestive
Carotid artery disease
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Cataract (clouding of the lens inside the eye)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Deafness neurosensory
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

What are the existing conditions these people have? *

Prostate Cancer Metastatic: 8 people, 25.00%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 12.50%
T-Cell Prolymphocytic Leukaemia (a aggressive type of t cell cancer): 3 people, 9.38%
Breast Cancer Female: 3 people, 9.38%
B Precursor Type Acute Leukaemia (lymphoid cancer): 3 people, 9.38%
Type 2 Diabetes: 2 people, 6.25%
Staphylococcal Sepsis (blood infection by an infection with staphylococcus bacteria): 2 people, 6.25%
Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 2 people, 6.25%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 6.25%
Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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