Mobic and Vimovo drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Mobic (meloxicam) and Vimovo (esomeprazole magnesium; naproxen). Common drug interactions include drug hypersensitivity among females and chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people have when they take Mobic and Vimovo. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.
What is Mobic?
Mobic has active ingredients of meloxicam. It is often used in arthritis. eHealthMe is studying from 26,684 Mobic users. Check the latest studies of Mobic.
What is Vimovo?
Vimovo has active ingredients of esomeprazole magnesium; naproxen. It is often used in osteoarthritis. eHealthMe is studying from 9,608 Vimovo users. Check the latest studies of Vimovo.
34 people who take Mobic and Vimovo together, and have interactions are studied.

What are the common drug interactions of Mobic and Vimovo, by gender? *:
female:
- Drug hypersensitivity
- Arthralgia (joint pain)
- Joint swelling
- Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
- Chronic kidney disease
- Pain in extremity
- Renal failure (kidney dysfunction)
- Asthenia (weakness)
- Depression
- Dry eye (lack of adequate tears)
male:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Renal atrophy (wasting of kidney)
- Abdominal discomfort
- Muscle spasms (muscle contraction)
- Anxiety
- Arthralgia (joint pain)
- Breast cancer male
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Gastric disorder (disease of stomach)
What are the common drug interactions of Mobic and Vimovo, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Anxiety
- Arthralgia (joint pain)
- Breast cancer male
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Bruxism (habitual grinding of the teeth, typically during sleep)
- Confusional state
- Drug detoxification
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
- Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
- Herpes simplex (herpes simplex is a common viral infection)
50-59:
- Arthralgia (joint pain)
- Joint swelling
- Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
- Chronic kidney disease
- Pain in extremity
- Asthenia (weakness)
- Depression
- Dry eye (lack of adequate tears)
- Dry mouth
- Dyspepsia (indigestion)
60+:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Proteinuria (presence of protein in the urine)
- Renal atrophy (wasting of kidney)
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Eyelid disorder
- Infection
- Oedema peripheral (superficial swelling)
- Renal injury (kidney injury)
- Nephropathy (damage to or disease of a kidney)
What are the existing conditions these people have? *
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 20 people, 58.82%
- Pain: 17 people, 50.00%
- High Blood Pressure: 15 people, 44.12%
- Fluid Retention (an abnormal accumulation of fluid in the blood): 9 people, 26.47%
- Renal Disorder (kidney disease): 9 people, 26.47%
- Chest Pain: 9 people, 26.47%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 9 people, 26.47%
- Constipation: 9 people, 26.47%
- Indigestion: 9 people, 26.47%
- Stress And Anxiety: 9 people, 26.47%
* Approximation only. Some reports may have incomplete information.
Do you take Mobic and Vimovo?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Mobic and Vimovo:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Mobic:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Vimovo:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Mobic and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Vimovo and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Lai SW, Lin CL, Liao KF, "Association of Meloxicam Use with the Risk of Acute Pancreatitis: A Case–Control Study", Clinical drug investigation, 2015 Oct .
- Lai SW, Lin CL, Liao KF, "Association of Meloxicam Use with the Risk of Acute Pancreatitis: A Case–Control Study", Clinical drug investigation, 2015 Oct .
How the study uses the data?
The study uses data from the FDA. It is based on meloxicam and esomeprazole magnesium; naproxen (the active ingredients of Mobic and Vimovo, respectively), and Mobic and Vimovo (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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