Modafinil and Benlysta drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Modafinil (modafinil) and Benlysta (belimumab). Common drug interactions include lymphadenopathy among females and abdominal distension among males.
The phase IV clinical study analyzes what interactions people have when they take Modafinil and Benlysta. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.
What is Modafinil?
Modafinil has active ingredients of modafinil. It is often used in narcolepsy. eHealthMe is studying from 20,805 Modafinil users. Check the latest studies of Modafinil.
What is Benlysta?
Benlysta has active ingredients of belimumab. It is often used in systemic lupus erythematosus. eHealthMe is studying from 23,528 Benlysta users. Check the latest studies of Benlysta.
26 people who take Modafinil and Benlysta together, and have interactions are studied.

What are the common drug interactions of Modafinil and Benlysta, by gender? *:
female:
- Lymphadenopathy (disease or enlargement of lymph nodes)
- Anxiety
- Hallucination (an experience involving the perception of something not present)
- Thyroid neoplasm (tumour of thyroid)
- Abdominal pain upper
- Pyrexia (fever)
- Abdominal distension
- Hepatic enzyme increased
- Nausea (feeling of having an urge to vomit)
- Suicidal ideation
male:
- Abdominal distension
- Abdominal pain upper
- Nausea (feeling of having an urge to vomit)
- Neoplasm progression (growth of tumour)
- Pleurisy (inflammation of the pleurae, which causes pain when breathing)
- Pneumonia
- Pyrexia (fever)
- Thyroid neoplasm (tumour of thyroid)
- Alanine aminotransferase increased
- Aspartate aminotransferase increased
What are the common drug interactions of Modafinil and Benlysta, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Depression
- Suicidal ideation
- Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
- Drug hypersensitivity
- Rash
40-49:
- Lymphadenopathy (disease or enlargement of lymph nodes)
- Hallucination (an experience involving the perception of something not present)
- Thyroid neoplasm (tumour of thyroid)
- Anxiety
- Abdominal pain upper
- Pyrexia (fever)
- Abdominal distension
- Nausea (feeling of having an urge to vomit)
- Aspartate aminotransferase increased
- Gamma-glutamyltransferase increased
50-59:
- Generalised erythema (redness of the skin all over the body)
- Injection site erythema (redness at injection site)
- Injection site pain
- Nasal odour
- Rash macular (small, flat red spots)
- Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
60+:
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Cerebrospinal fluid leakage
- Drug ineffective
- Dural tear
- Exostosis (formation of new bone on the surface of a bone)
- Hospitalisation
- Incoherent (talking in a confused and unclear way)
- Lumbar radiculopathy (radicular pain in the low back and legs)
- Neuralgia (pain in one or more nerves)
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
What are the existing conditions these people have? *
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 26.92%
* Approximation only. Some reports may have incomplete information.
Do you take Modafinil and Benlysta?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Modafinil and Benlysta:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Modafinil:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Benlysta:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Modafinil and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Benlysta and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Lopes E, Pereira D, da Silva Behrens NS, de Almeida Fonseca H, Calvancanti PO, de Araújo Lima TF, Pradella-Hallinan M, Castro J, Tufik S, Coelho FM, "Cataplexy as a side effect of modafinil in a patient without narcolepsy", Sleep Science, 2014 Mar .
- Lopes E, Pereira D, da Silva Behrens NS, de Almeida Fonseca H, Calvancanti PO, de Araújo Lima TF, Pradella-Hallinan M, Castro J, Tufik S, Coelho FM, "Cataplexy as a side effect of modafinil in a patient without narcolepsy", Sleep Science, 2014 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on modafinil and belimumab (the active ingredients of Modafinil and Benlysta, respectively), and Modafinil and Benlysta (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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