Modafinil and Ditropan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Modafinil (modafinil) and Ditropan (oxybutynin chloride). Common drug interactions include bipolar disorder among females and urinary tract infection among males.

The phase IV clinical study analyzes what interactions people have when they take Modafinil and Ditropan. It is created by eHealthMe based on reports of 76 people who take the same drugs from the FDA, and is updated regularly.

What is Modafinil?

Modafinil has active ingredients of modafinil. It is often used in narcolepsy. eHealthMe is studying from 20,805 Modafinil users. Check the latest studies of Modafinil.

What is Ditropan?

Ditropan has active ingredients of oxybutynin chloride. It is often used in urge incontinence. eHealthMe is studying from 11,799 Ditropan users. Check the latest studies of Ditropan.



On Aug, 08, 2026

76 people who take Modafinil and Ditropan together, and have interactions are studied.

Modafinil and Ditropan drug interactions.

What are the common drug interactions of Modafinil and Ditropan, by gender? *:

female:

  1. Bipolar disorder (mood disorder)
  2. Bladder irritation
  3. Blood glucose increased
  4. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  5. Cholecystitis (infection of gallbladder)
  6. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  7. Chronic kidney disease
  8. Cough
  9. Depression
  10. Diabetes mellitus non-insulin-dependent

male:

  1. Urinary tract infection
  2. Anxiety
  3. Gastric ulcer (stomach ulcer)
  4. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  5. Glossodynia (a burning or painful sensation in the tongue)
  6. Hypertonic bladder (bladder-storage function that causes a sudden urge to urinate)
  7. Hypoaesthesia (reduced sense of touch or sensation)
  8. Injury
  9. Labyrinthitis (inflammation of the labyrinth or inner ear)
  10. Lobar pneumonia (a form of pneumonia that affects a large and continuous area of the lobe of a lung)

What are the common drug interactions of Modafinil and Ditropan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Breast cancer metastatic
  2. Anaemia (lack of blood)
  3. Cholecystitis (infection of gallbladder)
  4. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  5. Diabetes mellitus non-insulin-dependent
  6. Hepatitis c
  7. Hypertension (high blood pressure)
  8. Insomnia (sleeplessness)
  9. Obesity (having too much body fat)
  10. Platelet count decreased

40-49:

  1. Anxiety
  2. Drug hypersensitivity
  3. Memory impairment
  4. Nasal disorder (diseases of nose)
  5. Schizoaffective disorder (a mental disorder characterized by disordered thought)
  6. Stress
  7. Urinary retention (the inability to completely or partially empty the bladder)
  8. Weight decreased
  9. Alopecia (absence of hair from areas of the body)
  10. Arthralgia (joint pain)

50-59:

  1. Fall
  2. Anal fistula
  3. Bladder neoplasm (bladder tumour)
  4. Blood pressure increased
  5. Drug ineffective
  6. Dry mouth
  7. Fibromyalgia (a long-term condition which causes pain all over the body)
  8. Hip fracture
  9. Post procedural complication
  10. Surgery

60+:

  1. Fall
  2. Urinary tract infection
  3. Delirium (wild excitement)
  4. Drug dependence
  5. Aspartate aminotransferase increased
  6. Bacterial infection
  7. Bladder irritation
  8. Blood glucose increased
  9. Blood potassium decreased
  10. Breast cancer

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 28 people, 36.84%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 18 people, 23.68%
  3. Drowsiness: 11 people, 14.47%
  4. Parkinson's Disease: 8 people, 10.53%
  5. Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 8 people, 10.53%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 10.53%
  7. Diabetes: 8 people, 10.53%
  8. Urinary Tract Infection: 7 people, 9.21%
  9. Insomnia (sleeplessness): 7 people, 9.21%
  10. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 7 people, 9.21%

* Approximation only. Some reports may have incomplete information.

Do you take Modafinil and Ditropan?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Modafinil and Ditropan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Modafinil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ditropan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Modafinil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ditropan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on modafinil and oxybutynin chloride (the active ingredients of Modafinil and Ditropan, respectively), and Modafinil and Ditropan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: