Modafinil and Geodon drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Modafinil (modafinil) and Geodon (ziprasidone hydrochloride). Common drug interactions include insomnia among females and homicidal ideation among males.
The phase IV clinical study analyzes what interactions people have when they take Modafinil and Geodon. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.
What is Modafinil?
Modafinil has active ingredients of modafinil. It is often used in narcolepsy. eHealthMe is studying from 20,805 Modafinil users. Check the latest studies of Modafinil.
What is Geodon?
Geodon has active ingredients of ziprasidone hydrochloride. It is often used in bipolar disorder. eHealthMe is studying from 19,504 Geodon users. Check the latest studies of Geodon.
35 people who take Modafinil and Geodon together, and have interactions are studied.

What are the common drug interactions of Modafinil and Geodon, by gender? *:
female:
- Insomnia (sleeplessness)
- Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
- Anxiety
- Weight increased
- Choking (mechanical obstruction of the flow of air from the environment into the lungs)
- Colonoscopy
- Confusional state
- Death
- Dyspnoea (difficult or laboured respiration)
- Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain)
male:
- Homicidal ideation (thoughts about human killing another human)
- Insomnia (sleeplessness)
- Fatigue (feeling of tiredness)
- Gingival bleeding (bleeding gums)
- Muscle cramp (painful sensation caused by muscle contraction)
- Myalgia (muscle pain)
- Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
- Optic neuritis (optic nerve inflammation)
- Pain in extremity
- Pathological gambling
What are the common drug interactions of Modafinil and Geodon, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Homicidal ideation (thoughts about human killing another human)
- Insomnia (sleeplessness)
- Irritability
- Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
- Schizophrenia (a mental disorder characterized by a breakdown of thought processes)
- Executive dysfunction
- Fatigue (feeling of tiredness)
- Gingival bleeding (bleeding gums)
- Hypersensitivity
- Injury
30-39:
- Confusional state
- Death
- Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain)
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
- Insomnia (sleeplessness)
- Myositis (inflammation of the muscles)
- Night sweats (sweating in night)
- Obsessive rumination (thinking and worry or rumination is an inability to gain control over recurrent, distressing thoughts, images)
- Oral herpes (viral infection of mouth)
- Papilloma viral infection
40-49:
- Choking (mechanical obstruction of the flow of air from the environment into the lungs)
- Colonoscopy
- Hallucination (an experience involving the perception of something not present)
- Hysterectomy
- Insomnia (sleeplessness)
- Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
- Psychomotor hyperactivity (feelings of extreme restlessness)
- Visual disturbance
- Wheezing (a high-pitched whistling sound made while you breath)
- Headache (pain in head)
50-59:
n/a
60+:
n/a
What are the existing conditions these people have? *
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 9 people, 25.71%
- Hypersensitivity: 5 people, 14.29%
- Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 5 people, 14.29%
- Stress And Anxiety: 3 people, 8.57%
- Scoliosis (a medical condition in which a person's spine is curved from side to side): 3 people, 8.57%
- Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 8.57%
- Cough: 2 people, 5.71%
- Depression: 2 people, 5.71%
- Diabetes: 2 people, 5.71%
- Dyskinesia (abnormality or impairment of voluntary movement): 2 people, 5.71%
* Approximation only. Some reports may have incomplete information.
Do you take Modafinil and Geodon?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Modafinil and Geodon:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Modafinil:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Geodon:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Modafinil and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Geodon and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Lopes E, Pereira D, da Silva Behrens NS, de Almeida Fonseca H, Calvancanti PO, de Araújo Lima TF, Pradella-Hallinan M, Castro J, Tufik S, Coelho FM, "Cataplexy as a side effect of modafinil in a patient without narcolepsy", Sleep Science, 2014 Mar .
- Lopes E, Pereira D, da Silva Behrens NS, de Almeida Fonseca H, Calvancanti PO, de Araújo Lima TF, Pradella-Hallinan M, Castro J, Tufik S, Coelho FM, "Cataplexy as a side effect of modafinil in a patient without narcolepsy", Sleep Science, 2014 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on modafinil and ziprasidone hydrochloride (the active ingredients of Modafinil and Geodon, respectively), and Modafinil and Geodon (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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