Trulicity and Keppra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trulicity (dulaglutide) and Keppra (levetiracetam). Common drug interactions include alopecia among females and atrial fibrillation among males.

The phase IV clinical study analyzes what interactions people have when they take Trulicity and Keppra. It is created by eHealthMe based on reports of 54 people who take the same drugs from the FDA, and is updated regularly.

What is Trulicity?

Trulicity has active ingredients of dulaglutide. It is often used in weight loss. eHealthMe is studying from 77,529 Trulicity users. Check the latest studies of Trulicity.

What is Keppra?

Keppra has active ingredients of levetiracetam. It is often used in epilepsy. eHealthMe is studying from 73,504 Keppra users. Check the latest studies of Keppra.

On Jul, 12, 2026

54 people who take Trulicity and Keppra together, and have interactions are studied.

What are the common drug interactions of Trulicity and Keppra, by gender? *:

female:

Alopecia (absence of hair from areas of the body)
Blood glucose decreased
Fall
Fatigue (feeling of tiredness)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Hidradenitis (chronic disease of a type of sweat gland)
Impaired gastric emptying
Influenza
Injection site bruising
Injection site pain

male:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Acute respiratory failure
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hypertension (high blood pressure)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Loss of consciousness
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Odynophagia (painful swallowing, in the mouth (oropharynx) or oesophagus)

What are the common drug interactions of Trulicity and Keppra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Pulmonary haemorrhage (acute bleeding from the lung)
Death
Pneumonia
Streptococcal infection

30-39:

Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Blood glucose decreased
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Injection site bruising
Injection site pain
Pruritus (severe itching of the skin)

40-49:

Disturbance in attention
Hypercalcaemia (elevated calcium (ca+) level in the blood)
Hypernatraemia (an abnormally high plasma concentration of sodium ions)
Hypotension (abnormally low blood pressure)
Pneumonia
Respiratory failure (inadequate gas exchange by the respiratory system)
Urinary tract infection enterococcal
Anxiety
Depression
Fatigue (feeling of tiredness)

50-59:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Fall
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Nausea (feeling of having an urge to vomit)
Acute respiratory failure
Asthenia (weakness)
Barrett's oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach)
Chills (felling of cold)
Constipation
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

60+:

Acute respiratory failure
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cataract (clouding of the lens inside the eye)
Cerebral haemorrhage (bleeding within the brain)
Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
Chest pain
Diabetes mellitus inadequate control
Diarrhoea
Drug eruption (adverse drug reaction of the skin)
Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

Type 2 Diabetes: 9 people, 16.67%
Diabetes: 9 people, 16.67%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 8 people, 14.81%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 8 people, 14.81%
Constipation: 5 people, 9.26%
Immunodeficiency Common Variable: 4 people, 7.41%
Depression: 4 people, 7.41%
Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands): 3 people, 5.56%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 5.56%
Chronic Inflammatory Demyelinating Polyradiculoneuropathy (long lasting infection of nerves outside brain and spinal cord): 3 people, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Trulicity and Keppra?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously