1. Home
  2. Analysis
  3. Modafinil
  4. L-tyrosine

Modafinil and L-tyrosine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Modafinil (modafinil) and L-tyrosine (tyrosine). Common drug interactions include cardiac disorder among females and dizziness among males.

The phase IV clinical study analyzes what interactions people have when they take Modafinil and L-tyrosine. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Modafinil?

Modafinil has active ingredients of modafinil. It is often used in narcolepsy. eHealthMe is studying from 20,805 Modafinil users. Check the latest studies of Modafinil.

What is L-tyrosine?

L-tyrosine has active ingredients of tyrosine. It is often used in hypothyroidism. eHealthMe is studying from 312 L-tyrosine users. Check the latest studies of L-tyrosine.

On Jul, 06, 2026

11 people who take Modafinil and L-tyrosine together, and have interactions are studied.

Modafinil and L-tyrosine drug interactions.

What are the common drug interactions of Modafinil and L-Tyrosine, by gender? *:

female:

  1. Cardiac disorder
  2. Hangover
  3. Headache (pain in head)
  4. Heart rate increased
  5. Hepatic pain (pain in liver)
  6. Injection site urticaria (rash of round, red welts on the skin at injection site)
  7. Insomnia (sleeplessness)
  8. Memory impairment
  9. Muscle spasms (muscle contraction)
  10. Myalgia (muscle pain)

male:

  1. Dizziness
  2. Drug ineffective
  3. Fatigue (feeling of tiredness)
  4. Nausea (feeling of having an urge to vomit)
  5. Surgery
  6. Vision blurred
  7. Visual impairment

What are the common drug interactions of Modafinil and L-Tyrosine, by age (0-1 to 60+)? *:

0-1:

  1. Drug ineffective
  2. Fatigue (feeling of tiredness)
  3. Nausea (feeling of having an urge to vomit)
  4. Vision blurred
  5. Visual impairment
  6. Dizziness

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Back pain
  2. Headache (pain in head)
  3. Hepatic pain (pain in liver)
  4. Injection site urticaria (rash of round, red welts on the skin at injection site)
  5. Muscle spasms (muscle contraction)
  6. Myalgia (muscle pain)
  7. Renal pain (kidney pain)

60+:

  1. Hangover
  2. Peripheral swelling

What are the existing conditions these people have? *

  1. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 45.45%
  2. Depression: 3 people, 27.27%
  3. Stress And Anxiety: 1 person, 9.09%
  4. Restless Leg Syndrome (a powerful urge to move your legs): 1 person, 9.09%
  5. Peripheral Swelling: 1 person, 9.09%
  6. Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 1 person, 9.09%
  7. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 9.09%
  8. Migraine (headache): 1 person, 9.09%
  9. Ill-Defined Disorder: 1 person, 9.09%
  10. Hypersensitivity: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Modafinil and L-tyrosine?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Modafinil and L-tyrosine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Modafinil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of L-tyrosine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Modafinil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between L-tyrosine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on modafinil and tyrosine (the active ingredients of Modafinil and L-tyrosine, respectively), and Modafinil and L-tyrosine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe:

© 2026 eHealthMe.com. All rights reserved. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy.