Monoket and Pradaxa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Monoket (isosorbide mononitrate) and Pradaxa (dabigatran etexilate mesylate). Common drug interactions include parkinsonism among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Monoket and Pradaxa. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Monoket?

Monoket has active ingredients of isosorbide mononitrate. eHealthMe is studying from 623 Monoket users. Check the latest studies of Monoket.

What is Pradaxa?

Pradaxa has active ingredients of dabigatran etexilate mesylate. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 86,906 Pradaxa users. Check the latest studies of Pradaxa.



On Jul, 12, 2026

13 people who take Monoket and Pradaxa together, and have interactions are studied.

Monoket and Pradaxa drug interactions.

What are the common drug interactions of Monoket and Pradaxa, by gender? *:

female:

  1. Parkinsonism (degenerative disorder of the central nervous system characterized by tremor and impaired muscular coordination)
  2. Asthenia (weakness)
  3. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
  4. Cerebral haemorrhage (bleeding within the brain)
  5. Dyspnoea (difficult or laboured respiration)
  6. Hypertension (high blood pressure)
  7. Hypokalaemia (low potassium)
  8. Malaise (a feeling of general discomfort or uneasiness)

male:

  1. Anaemia (lack of blood)
  2. Cardioversion
  3. Haematochezia (passage of stools containing blood)
  4. Haematoma (collection of blood outside the blood vessels)
  5. Hypokalaemia (low potassium)
  6. Hypokalaemic syndrome (serum concentration of potassium <3.5)
  7. Melaena (the passage of black, tarry stools)
  8. Retinal vein thrombosis (clot formation in small veins that carry blood away from the retina)
  9. Renal failure (kidney dysfunction)
  10. Abdominal pain

What are the common drug interactions of Monoket and Pradaxa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Anaemia (lack of blood)
  2. Cardioversion
  3. Dyspnoea exertional (breathlessness or shortness of breath)
  4. Haematinuria (blood in your urine)
  5. Haematochezia (passage of stools containing blood)
  6. Hypertension (high blood pressure)
  7. Hypokalaemic syndrome (serum concentration of potassium <3.5)
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Melaena (the passage of black, tarry stools)
  10. Parkinsonism (degenerative disorder of the central nervous system characterized by tremor and impaired muscular coordination)

What are the existing conditions these people have? *

  1. Behavioral And Psychiatric Symptoms Of Dementia: 2 people, 15.38%
  2. Stable Angina (a constant chest pain): 1 person, 7.69%
  3. Rickets (softening of bones): 1 person, 7.69%
  4. Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 1 person, 7.69%
  5. High Blood Cholesterol: 1 person, 7.69%
  6. Gastritis Erosive (a break in the surface layer of the membrane lining the stomach with infection): 1 person, 7.69%
  7. Coronary Artery Stenosis (narrowing of coronary artery): 1 person, 7.69%
  8. Constipation: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Monoket and Pradaxa?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Monoket and Pradaxa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Monoket:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Pradaxa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Monoket and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pradaxa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on isosorbide mononitrate and dabigatran etexilate mesylate (the active ingredients of Monoket and Pradaxa, respectively), and Monoket and Pradaxa (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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