Morphine sulfate and Accolate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Morphine sulfate (morphine sulfate) and Accolate (zafirlukast). Common drug interactions include costochondritis among females and blood potassium decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Morphine sulfate and Accolate. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Morphine sulfate?

Morphine sulfate has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 87,262 Morphine sulfate users. Check the latest studies of Morphine sulfate.

What is Accolate?

Accolate has active ingredients of zafirlukast. It is often used in asthma. eHealthMe is studying from 4,220 Accolate users. Check the latest studies of Accolate.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 15, 2026

14 people who take Morphine sulfate and Accolate together, and have interactions are studied.

Morphine sulfate and Accolate drug interactions.

What are the common drug interactions of Morphine Sulfate and Accolate, by gender? *:

female:

  1. Costochondritis (chest wall pain)
  2. Cystocele (a condition that occurs when the tough fibrous wall between a woman's bladder and her vagina is torn by childbirth)
  3. Deformity (disfigurement)
  4. Depressed mood
  5. Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
  6. Diarrhoea
  7. Disability
  8. Dizziness
  9. Drug dependence
  10. Drug level above therapeutic

male:

  1. Blood potassium decreased
  2. Abdominal discomfort
  3. Injury
  4. Nausea (feeling of having an urge to vomit)
  5. Nocturia (the need to get up in the night to urinate)
  6. Overdose
  7. Prostatitis (inflammation of the prostate gland)
  8. Rectal haemorrhage (bleeding from anus)
  9. Renal cyst (kidney cyst)
  10. Somnolence (a state of near-sleep, a strong desire for sleep)

What are the common drug interactions of Morphine Sulfate and Accolate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Sensation of foreign body
  2. Sinus congestion (blockage of sinus)

30-39:

  1. Blood potassium decreased
  2. Abdominal discomfort
  3. Anxiety
  4. Chest discomfort
  5. Dysphonia (speech disorder attributable to a disorder of phonation)
  6. Emotional distress
  7. Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
  8. Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
  9. Haematochezia (passage of stools containing blood)
  10. Increased upper airway secretion

40-49:

n/a

50-59:

  1. Renal disorder (kidney disease)

60+:

  1. Anaemia (lack of blood)
  2. Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
  3. Pelvic pain
  4. Pneumonia
  5. Rigors (an episode of shaking or exaggerated shivering)
  6. Arthralgia (joint pain)
  7. Asthenia (weakness)
  8. Blood pressure decreased
  9. Cardiac arrest
  10. Cardiac failure congestive

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 14.29%
  2. Stress And Anxiety: 1 person, 7.14%
  3. Menopause (end of monthly cycles in women): 1 person, 7.14%
  4. Arthropathy: 1 person, 7.14%
  5. Arthropod Sting (arthropod bite): 1 person, 7.14%
  6. Breakthrough Pain: 1 person, 7.14%
  7. Fabry's Disease (build up of a particular type of fat, called globotriaosylceramide, in the body's cells): 1 person, 7.14%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.14%
  9. High Blood Cholesterol: 1 person, 7.14%
  10. Immunodeficiency Common Variable: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Morphine sulfate and Accolate?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Morphine sulfate and Accolate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Morphine sulfate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Accolate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Morphine sulfate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Accolate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on morphine sulfate and zafirlukast (the active ingredients of Morphine sulfate and Accolate, respectively), and Morphine sulfate and Accolate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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