Morphine and Firdapse drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Morphine (morphine sulfate) and Firdapse (amifampridine). Common drug interactions include muscular weakness among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Morphine and Firdapse. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Morphine?

Morphine has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 182,914 Morphine users. Check the latest studies of Morphine.

What is Firdapse?

Firdapse has active ingredients of amifampridine. eHealthMe is studying from 2,112 Firdapse users. Check the latest studies of Firdapse.

On Aug, 09, 2026

23 people who take Morphine and Firdapse together, and have interactions are studied.

Morphine and Firdapse drug interactions.

What are the common drug interactions of Morphine and Firdapse, by gender? *:

female:

Muscular weakness (muscle weakness)
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Pain in extremity
Cough
Limb discomfort (discomfort in leg)
Nausea (feeling of having an urge to vomit)
Constipation
Dizziness
Feeling cold
Gait disturbance

male:

Pneumonia
Weight increased
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect)
Depression
Drug hypersensitivity
Overdose
Unresponsive to stimuli
Headache (pain in head)
Neoplasm malignant (cancer tumour)

What are the common drug interactions of Morphine and Firdapse, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abdominal pain upper
Body temperature increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cough
Hyperhidrosis (abnormally increased sweating)
Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect)
Blood glucose increased
Blood pressure increased
Upper respiratory tract infection
Cartilage injury

50-59:

Drug ineffective

60+:

Pneumonia
Asthenia (weakness)
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Myalgia (muscle pain)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Weight decreased
Depression
Drug hypersensitivity

What are the existing conditions these people have? *

Lambert-Eaton Syndrome (this means your immune system mistakenly targets healthy cells and tissues in the body): 23 people, 100.00%

* Approximation only. Some reports may have incomplete information.

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