Morphine and Hibiclens drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Morphine (morphine sulfate) and Hibiclens (chlorhexidine gluconate). Common drug interactions include pulmonary arterial hypertension among females and encephalopathy among males.

The phase IV clinical study analyzes what interactions people have when they take Morphine and Hibiclens. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Morphine?

Morphine has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 182,914 Morphine users. Check the latest studies of Morphine.

What is Hibiclens?

Hibiclens has active ingredients of chlorhexidine gluconate. eHealthMe is studying from 536 Hibiclens users. Check the latest studies of Hibiclens.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

32 people who take Morphine and Hibiclens together, and have interactions are studied.

Morphine and Hibiclens drug interactions.

What are the common drug interactions of Morphine and Hibiclens, by gender? *:

female:

Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
Pulmonary embolism (blockage of the main artery of the lung)
Renal failure (kidney dysfunction)
Thrombophlebitis superficial (swelling (inflammation) of a superficial vein caused by a blood clot)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Abscess limb (limb infection)
Anal abscess
Cardiac failure
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Cellulitis (infection under the skin)

male:

Encephalopathy (functioning of the brain is affected by some agent or condition)
Renal failure acute (rapid kidney dysfunction)
Haematoma (collection of blood outside the blood vessels)
Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
Hepatic failure (liver failure)
Liver disorder (liver diseases)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Pneumonia

What are the common drug interactions of Morphine and Hibiclens, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Atelectasis (partial or complete collapse of the lung)
Dyspnoea (difficult or laboured respiration)
Pain in extremity
Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
Pulmonary embolism (blockage of the main artery of the lung)
Thrombophlebitis superficial (swelling (inflammation) of a superficial vein caused by a blood clot)
Cardiac failure
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Injury

40-49:

Death
Palpitations (feelings or sensations that your heart is pounding or racing)
Syncope (loss of consciousness with an inability to maintain postural tone)

50-59:

Pulmonary hypertension (increase in blood pressure in the lung artery)
Renal failure acute (rapid kidney dysfunction)
Septic shock (shock due to blood infection)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Pneumonia
Serratia bacteraemia (bacterial blood infection)
Staphylococcal bacteraemia (a bacterial infection of blood)
Thrombocytopenia (decrease of platelets in blood)
Thrombosis (formation of a blood clot inside a blood vessel)

60+:

Hypertension (high blood pressure)
Oedema peripheral (superficial swelling)
Blood uric acid increased
Breast mass
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Cough
Defaecation urgency (a sudden compelling urge to defecate)
Dental caries
Dermatitis allergic (inflammation of the skin due allergic reaction)
Diarrhoea

What are the existing conditions these people have? *

High Blood Pressure: 4 people, 12.50%
Thyroid Cancer: 3 people, 9.38%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 9.38%
Renal Disorder (kidney disease): 2 people, 6.25%
Osteoporosis (bones weak and more likely to break): 2 people, 6.25%
Joint Pain: 2 people, 6.25%
Hiv Infection: 2 people, 6.25%
Gastric Ulcer (stomach ulcer): 2 people, 6.25%
Gastric Disorder (disease of stomach): 2 people, 6.25%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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