Morphine and Librax drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Morphine (morphine sulfate) and Librax (chlordiazepoxide hydrochloride; clidinium bromide). Common drug interactions include chronic left ventricular failure among females and amnesia among males.
The phase IV clinical study analyzes what interactions people have when they take Morphine and Librax. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.
What is Morphine?
Morphine has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 182,913 Morphine users. Check the latest studies of Morphine.
What is Librax?
Librax has active ingredients of chlordiazepoxide hydrochloride; clidinium bromide. eHealthMe is studying from 660 Librax users. Check the latest studies of Librax.
19 people who take Morphine and Librax together, and have interactions are studied.

What are the common drug interactions of Morphine and Librax, by gender? *:
female:
- Chronic left ventricular failure (long lasting functional impairment of left ventricle of heart)
- Dry eye (lack of adequate tears)
- Headache (pain in head)
- Oral pain
- Pain in extremity
- Pain in jaw
- Renal disorder (kidney disease)
- Diarrhoea
- Drug hypersensitivity
- Dry mouth
male:
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Chest pain
- Confusional state
- Insomnia (sleeplessness)
- Restless legs syndrome (a powerful urge to move your legs)
- Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
- Large intestine perforation (hole in large intestine)
- Rectal perforation (tear or hole in rectum)
What are the common drug interactions of Morphine and Librax, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Arthralgia (joint pain)
- Blood thyroid stimulating hormone decreased
- Constipation
- Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
- Diarrhoea
- Fatigue (feeling of tiredness)
- Glycosylated haemoglobin increased
- Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
- Metabolic disorder (an abnormal function and pattern of body fat. insulin resistance refers to the diminished ability of cells to respond to the action of insulin in promoting the transport of the sugar glucose, from blood into muscles and other tissues)
- Ovarian cyst (fluid filled sac of the ovary)
30-39:
n/a
40-49:
n/a
50-59:
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Chest pain
- Confusional state
- Insomnia (sleeplessness)
- Restless legs syndrome (a powerful urge to move your legs)
- Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
- Abdominal discomfort
- Chest discomfort
- Escherichia urinary tract infection (urinary tract infection by escherichia coli)
60+:
- Cataract (clouding of the lens inside the eye)
- Chronic kidney disease
- Urinary tract infection
- Death
- Decreased appetite
- Diarrhoea
- Large intestine perforation (hole in large intestine)
- Malaise (a feeling of general discomfort or uneasiness)
- Rectal perforation (tear or hole in rectum)
- Renal failure (kidney dysfunction)
What are the existing conditions these people have? *
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 15.79%
- Breast Cancer: 3 people, 15.79%
- Transitional Cell Carcinoma (cancer tumour inner most layer of urinary system): 2 people, 10.53%
- Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 2 people, 10.53%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 10.53%
- High Blood Pressure: 2 people, 10.53%
- Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 1 person, 5.26%
- Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract): 1 person, 5.26%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.26%
- Drowsiness: 1 person, 5.26%
* Approximation only. Some reports may have incomplete information.
Do you take Morphine and Librax?
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- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Morphine and Librax:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Morphine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Librax:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Morphine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Librax and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Rasmy A, Rahal M, Kisana M, Ahmad S, Salah A, "Morphine induced thrombocytopenia: A case report", Journal of Case Reports and Images in Oncology, 2015 Dec .
- Rasmy A, Rahal M, Kisana M, Ahmad S, Salah A, "Morphine induced thrombocytopenia: A case report", Journal of Case Reports and Images in Oncology, 2015 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on morphine sulfate and chlordiazepoxide hydrochloride; clidinium bromide (the active ingredients of Morphine and Librax, respectively), and Morphine and Librax (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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