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Morphine and Oxervate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Morphine (morphine sulfate) and Oxervate (cenegermin-bkbj). Common drug interactions include eye pain among females and eye pain among males.

The phase IV clinical study analyzes what interactions people have when they take Morphine and Oxervate. It is created by eHealthMe based on reports of 63 people who take the same drugs from the FDA, and is updated regularly.

What is Morphine?

Morphine has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 182,913 Morphine users. Check the latest studies of Morphine.

What is Oxervate?

Oxervate has active ingredients of cenegermin-bkbj. eHealthMe is studying from 7,219 Oxervate users. Check the latest studies of Oxervate.

On Jul, 15, 2026

63 people who take Morphine and Oxervate together, and have interactions are studied.

Morphine and Oxervate drug interactions.

What are the common drug interactions of Morphine and Oxervate, by gender? *:

female:

  1. Eye pain
  2. Hospitalisation
  3. Eyelid pain
  4. Eye irritation
  5. Vision blurred
  6. Eye swelling
  7. Ocular discomfort (a generic expression when there is lack of ease in/about the eyes)
  8. Ocular hyperaemia (an abnormally large amount of blood in eye)
  9. Drug hypersensitivity
  10. Dry eye (lack of adequate tears)

male:

  1. Eye pain
  2. Lacrimation increased
  3. Eyelid pain
  4. Intestinal obstruction
  5. Vision blurred
  6. Vomiting
  7. Fall
  8. Contusion (a type of hematoma of tissue in which capillaries)
  9. Death
  10. Headache (pain in head)

What are the common drug interactions of Morphine and Oxervate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Hospitalisation
  2. Blood calcium decreased
  3. Drug hypersensitivity
  4. Eye pain
  5. Eye swelling
  6. Hypocalcaemia (levels of calcium in blood serum are abnormally low)
  7. Multiple fractures
  8. Periorbital oedema (swelling around the eyes)
  9. Quality of life decreased
  10. Road traffic accident

60+:

  1. Eye pain
  2. Ocular hyperaemia (an abnormally large amount of blood in eye)
  3. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  4. Drug ineffective
  5. Intestinal obstruction
  6. Death
  7. Dizziness
  8. Eye infection
  9. Eye swelling
  10. Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)

What are the existing conditions these people have? *

  1. Neurotrophic Keratopathy (decreased corneal sensitivity and poor corneal healing): 58 people, 92.06%
  2. Hypoaesthesia Eye (reduced sense of touch or sensation on eyes): 6 people, 9.52%
  3. Ulcerative Keratitis (ulcerative inflammation of the cornea): 5 people, 7.94%

* Approximation only. Some reports may have incomplete information.

Do you take Morphine and Oxervate?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Morphine and Oxervate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Morphine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Oxervate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Morphine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Oxervate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on morphine sulfate and cenegermin-bkbj (the active ingredients of Morphine and Oxervate, respectively), and Morphine and Oxervate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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