Morphine and Pentoxifylline drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Morphine (morphine sulfate) and Pentoxifylline (pentoxifylline). Common drug interactions include obstruction among females and confusional state among males.

The phase IV clinical study analyzes what interactions people have when they take Morphine and Pentoxifylline. It is created by eHealthMe based on reports of 94 people who take the same drugs from the FDA, and is updated regularly.

What is Morphine?

Morphine has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 182,913 Morphine users. Check the latest studies of Morphine.

What is Pentoxifylline?

Pentoxifylline has active ingredients of pentoxifylline. eHealthMe is studying from 5,997 Pentoxifylline users. Check the latest studies of Pentoxifylline.

On Jul, 26, 2026

94 people who take Morphine and Pentoxifylline together, and have interactions are studied.

Morphine and Pentoxifylline drug interactions.

What are the common drug interactions of Morphine and Pentoxifylline, by gender? *:

female:

Obstruction
Drug intolerance (drug sensitivity)
Anxiety
Chills (felling of cold)
Drug tolerance decreased
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
Hyperhidrosis (abnormally increased sweating)
Myalgia (muscle pain)
Tremor (trembling or shaking movements in one or more parts of your body)
Cellulitis (infection under the skin)

male:

Confusional state
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Cataract (clouding of the lens inside the eye)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Diarrhoea
Drug intolerance (drug sensitivity)
Hypersensitivity
Hypertension (high blood pressure)
Klebsiella sepsis (klebsiella causes a potentially fatal whole-body inflammation)
Malaise (a feeling of general discomfort or uneasiness)

What are the common drug interactions of Morphine and Pentoxifylline, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Peripheral ischaemia (impaired circulation to an extremity)
Drug abuser
Ischaemia (insufficient supply of blood to an organ, usually due to a blocked artery)
Necrosis (the death of body tissue)
Oedema peripheral (superficial swelling)

40-49:

Chest pain
Chronic kidney disease
Nausea (feeling of having an urge to vomit)
Renal failure (kidney dysfunction)
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Headache (pain in head)
Pneumonia
Abdominal discomfort

50-59:

Drug screen positive
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Haemoglobin decreased
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Infection
Lethargy (tiredness)
Loss of consciousness
Overdose
Drug hypersensitivity
Duodenal ulcer

60+:

Asthenia (weakness)
Drug ineffective
Confusional state
Drug tolerance decreased
Myalgia (muscle pain)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
Anxiety
Chills (felling of cold)
Hyperhidrosis (abnormally increased sweating)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 12.77%
Back Pain: 11 people, 11.70%
High Blood Pressure: 8 people, 8.51%
Stress And Anxiety: 7 people, 7.45%
Muscle Aches (muscle pain): 6 people, 6.38%
Type 2 Diabetes: 5 people, 5.32%
Small Cell Lung Cancer Extensive Stage (small cell lung cancer that has spread (metastasized) to other regions of the body such as another lobe of the lung or the brain): 5 people, 5.32%
Peripheral Ischaemia (impaired circulation to an extremity): 5 people, 5.32%
Depression: 5 people, 5.32%

* Approximation only. Some reports may have incomplete information.

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