Morphine and Romazicon drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Morphine (morphine sulfate) and Romazicon (flumazenil). Common drug interactions include dizziness among females and hypotension among males.

The phase IV clinical study analyzes what interactions people have when they take Morphine and Romazicon. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Morphine?

Morphine has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 182,913 Morphine users. Check the latest studies of Morphine.

What is Romazicon?

Romazicon has active ingredients of flumazenil. eHealthMe is studying from 182 Romazicon users. Check the latest studies of Romazicon.



On Jul, 20, 2026

48 people who take Morphine and Romazicon together, and have interactions are studied.

Morphine and Romazicon drug interactions.

What are the common drug interactions of Morphine and Romazicon, by gender? *:

female:

  1. Dizziness
  2. Dysphagia (a condition in which swallowing is difficult or painful)
  3. Injury
  4. Osteomyelitis (infection of bone)
  5. Osteopenia (a condition where bone mineral density is lower than normal)
  6. Depression
  7. Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
  8. Renal failure (kidney dysfunction)
  9. Swelling
  10. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

male:

  1. Hypotension (abnormally low blood pressure)
  2. Nausea (feeling of having an urge to vomit)
  3. Anaemia (lack of blood)
  4. Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
  5. Aortic valve replacement
  6. Asthenia (weakness)
  7. Cardiac valve disease (heart valve disease)
  8. Death
  9. Gastric infection (infection of stomach)
  10. Haemoglobin decreased

What are the common drug interactions of Morphine and Romazicon, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Blood sodium decreased

20-29:

n/a

30-39:

n/a

40-49:

  1. Abdominal pain
  2. Fatigue (feeling of tiredness)
  3. Abdominal distension
  4. Pyrexia (fever)
  5. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  6. Chronic kidney disease
  7. Depression
  8. Device dislocation
  9. Dysmenorrhoea (painful menstruation)
  10. Fungaemia (fungi circulate in the blood)

50-59:

  1. Oral disorder (mouth disease)
  2. Osteomyelitis chronic (long lasting infection of bone marrow)
  3. Weight increased
  4. Wrist fracture
  5. Appetite disorder (abnormal eating habits)
  6. Chills (felling of cold)
  7. Dyspepsia (indigestion)
  8. Incontinence (lack of moderation or self-control)
  9. Osteoradionecrosis (irradiation of bones causes damage to osteocytes and impairs the blood supply)
  10. Pyrexia (fever)

60+:

  1. Hypotension (abnormally low blood pressure)
  2. Pyrexia (fever)
  3. Multi-organ failure (multisystem organ failure)
  4. Neutropenia (an abnormally low number of neutrophils)
  5. Oral candidiasis (fungal infection of mouth)
  6. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  7. Platelet count decreased
  8. Rales (an abnormal respiratory sound characterized by fine crackles)
  9. Sepsis (a severe blood infection that can lead to organ failure and death)
  10. Abdominal neoplasm (cancer of the stomach)

What are the existing conditions these people have? *

  1. Lung Cancer - Non-Small Cell (lung cancer): 12 people, 25.00%
  2. Hypercalcaemia Of Malignancy (elevated calcium (ca+) level in the blood with cancer): 12 people, 25.00%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 22.92%
  4. Depression: 6 people, 12.50%
  5. Breast Cancer: 4 people, 8.33%
  6. Abdominal Pain: 4 people, 8.33%
  7. Urinary Tract Infection: 3 people, 6.25%
  8. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 6.25%
  9. Migraine Without Aura (headache without neurological problems): 3 people, 6.25%
  10. Hypotension (abnormally low blood pressure): 3 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Morphine and Romazicon?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Morphine and Romazicon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Morphine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Romazicon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Morphine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Romazicon and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on morphine sulfate and flumazenil (the active ingredients of Morphine and Romazicon, respectively), and Morphine and Romazicon (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: