Morphine and Xigduo xr drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Morphine (morphine sulfate) and Xigduo xr (dapagliflozin propanediol; metformin hydrochloride). Common drug interactions include necrotising fasciitis among females and sepsis among males.

The phase IV clinical study analyzes what interactions people have when they take Morphine and Xigduo xr. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Morphine?

Morphine has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 182,913 Morphine users. Check the latest studies of Morphine.

What is Xigduo xr?

Xigduo xr has active ingredients of dapagliflozin propanediol; metformin hydrochloride. eHealthMe is studying from 2,917 Xigduo xr users. Check the latest studies of Xigduo xr.

On Jul, 02, 2026

17 people who take Morphine and Xigduo xr together, and have interactions are studied.

Morphine and Xigduo xr drug interactions.

What are the common drug interactions of Morphine and Xigduo Xr, by gender? *:

female:

Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Sepsis (a severe blood infection that can lead to organ failure and death)
Cellulitis (infection under the skin)
Perineal abscess
Vulval abscess
Abscess limb (limb infection)
Perirectal abscess
Anal abscess
Genital abscess (build up of pus in genital)
Abscess (pus)

male:

Sepsis (a severe blood infection that can lead to organ failure and death)
Cellulitis (infection under the skin)
Scar
Tooth abscess (pus formation in tooth)
Abscess limb (limb infection)
Cellulitis of male external genital organ (infection of male genitals soft tissue)
Hypotension (abnormally low blood pressure)
Perirectal abscess
Renal failure (kidney dysfunction)
Septic shock (shock due to blood infection)

What are the common drug interactions of Morphine and Xigduo Xr, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Cellulitis (infection under the skin)
Groin abscess (pus in groin)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Nerve injury
Scar
Sepsis (a severe blood infection that can lead to organ failure and death)
Tooth abscess (pus formation in tooth)
Anal abscess
Genital abscess (build up of pus in genital)

40-49:

Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Sepsis (a severe blood infection that can lead to organ failure and death)
Cellulitis (infection under the skin)
Scrotal abscess (pus in scrotum)
Cellulitis gangrenous (localized inflammation of the soft or connective tissue with considerable mass of body tissue dies (necrosis))
Gangrene (body tissue dies)
Perineal abscess
Urinary tract infection
Vulval abscess
Vulval cellulitis (inflammation of skin around vagina)

50-59:

Sepsis (a severe blood infection that can lead to organ failure and death)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Abscess (pus)
Cellulitis (infection under the skin)
Groin abscess (pus in groin)
Anal abscess
Genital abscess (build up of pus in genital)
Perineal abscess
Perirectal abscess
Abscess limb (limb infection)

60+:

Abscess (pus)
Cellulitis (infection under the skin)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Perineal abscess
Blood bilirubin increased
Hepatic infection
Confusional state
Hypertension (high blood pressure)
Groin abscess (pus in groin)
Sepsis (a severe blood infection that can lead to organ failure and death)

What are the existing conditions these people have? *

Type 2 Diabetes: 14 people, 82.35%
Weight Decreased: 13 people, 76.47%
Hypotension (abnormally low blood pressure): 11 people, 64.71%
High Blood Pressure: 3 people, 17.65%
Diabetes: 3 people, 17.65%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 5.88%
Neuropathy Peripheral (surface nerve damage): 1 person, 5.88%
Nausea (feeling of having an urge to vomit): 1 person, 5.88%
Hepatocellular Carcinoma (liver cancer): 1 person, 5.88%
Gastric Cancer (stomach cancer): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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