Morphine and Zarxio drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Morphine (morphine sulfate) and Zarxio (filgrastim-sndz). Common drug interactions include blood magnesium decreased among females and dysphagia among males.

The phase IV clinical study analyzes what interactions people have when they take Morphine and Zarxio. It is created by eHealthMe based on reports of 67 people who take the same drugs from the FDA, and is updated regularly.

What is Morphine?

Morphine has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 182,913 Morphine users. Check the latest studies of Morphine.

What is Zarxio?

Zarxio has active ingredients of filgrastim-sndz. eHealthMe is studying from 3,250 Zarxio users. Check the latest studies of Zarxio.

On Jul, 21, 2026

67 people who take Morphine and Zarxio together, and have interactions are studied.

What are the common drug interactions of Morphine and Zarxio, by gender? *:

female:

Blood magnesium decreased
Decreased appetite
Ear pain
Fatigue (feeling of tiredness)
Haemoglobin decreased
Hepatic failure (liver failure)
Malignant neoplasm progression (cancer tumour came back)
Platelet count decreased
Vomiting
Weight decreased

male:

Dysphagia (a condition in which swallowing is difficult or painful)
Arthralgia (joint pain)
Bradycardia (abnormally slow heart action)
Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
C-reactive protein decreased
Cardiac arrest
Chills (felling of cold)
Coagulopathy (blood's ability to clot is impaired)
Confusional state
Conjunctival pigmentation (colour of conctiva)

What are the common drug interactions of Morphine and Zarxio, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Death

30-39:

Hospitalisation
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

40-49:

Hypoxia (low oxygen in tissues)
Lactic acidosis (low ph in body tissues)
Laryngeal oedema (swelling of larynx)
Mycoplasma test positive
Neuropathy peripheral (surface nerve damage)
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pericardial effusion (fluid around the heart)
Pleural effusion (water on the lungs)
Pulmonary oedema (fluid accumulation in the lungs)

50-59:

Anaemia (lack of blood)
Thrombocytopenia (decrease of platelets in blood)
Acute respiratory failure
Lymphocyte count decreased
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
Nausea (feeling of having an urge to vomit)
Abdominal pain upper
Blood magnesium decreased
Decreased appetite

60+:

Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
Alanine aminotransferase increased
Pneumonia
Thrombocytopenia (decrease of platelets in blood)
Death
Arthralgia (joint pain)
Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Febrile neutropenia (fever with reduced white blood cells)
Hyperchloraemia (an excess of chlorides in the blood)

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 24 people, 35.82%
Stress And Anxiety: 22 people, 32.84%
Insomnia (sleeplessness): 21 people, 31.34%
Hypokalemia (low potassium): 17 people, 25.37%
High Blood Pressure: 15 people, 22.39%
Multiple Myeloma (cancer of the plasma cells): 14 people, 20.90%
Abdominal Pain: 13 people, 19.40%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 13 people, 19.40%
Ovarian Cancer (cancer of ovary): 12 people, 17.91%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 17.91%

* Approximation only. Some reports may have incomplete information.

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