Mucinex and Divalproex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mucinex (guaifenesin) and Divalproex (divalproex sodium). Common drug interactions include chills among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Mucinex and Divalproex. It is created by eHealthMe based on reports of 78 people who take the same drugs from the FDA, and is updated regularly.

What is Mucinex?

Mucinex has active ingredients of guaifenesin. It is often used in cough. eHealthMe is studying from 29,749 Mucinex users. Check the latest studies of Mucinex.

What is Divalproex?

Divalproex has active ingredients of divalproex sodium. It is often used in bipolar disorder. eHealthMe is studying from 14,063 Divalproex users. Check the latest studies of Divalproex.

On Aug, 10, 2026

78 people who take Mucinex and Divalproex together, and have interactions are studied.

Mucinex and Divalproex drug interactions.

What are the common drug interactions of Mucinex and Divalproex, by gender? *:

female:

Chills (felling of cold)
Syncope (loss of consciousness with an inability to maintain postural tone)
Constipation
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Dyspepsia (indigestion)
Immune system disorder
Infusion site pain
Pain in extremity
Swelling
Wound

male:

Anxiety
Pain
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Hip arthroplasty
Rotator cuff repair
Spinal cord injury
Upper limb fracture
Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
Arteriovenous malformation
Bone disorder

What are the common drug interactions of Mucinex and Divalproex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Chronic kidney disease
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Thrombosis (formation of a blood clot inside a blood vessel)

30-39:

Chronic kidney disease
Fatigue (feeling of tiredness)
Hepatic enzyme increased
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Renal injury (kidney injury)

40-49:

Chronic kidney disease
Pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Bone density decreased
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Emotional distress
Hip arthroplasty
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Renal failure (kidney dysfunction)

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)
Gastric ulcer (stomach ulcer)
Suicidal ideation
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Fracture
Osteoporosis (bones weak and more likely to break)
Pain

60+:

Pneumonia
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Infusion site swelling
Sinusitis (inflammation of sinus)
Syncope (loss of consciousness with an inability to maintain postural tone)
Blood pressure decreased
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Immune system disorder
Pain
Swelling

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 17 people, 21.79%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 16 people, 20.51%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 12 people, 15.38%
Asthma: 11 people, 14.10%
Hypergammaglobulinaemia (elevated levels of gamma globulin): 9 people, 11.54%
Pain: 9 people, 11.54%
High Blood Pressure: 8 people, 10.26%
Depression: 7 people, 8.97%
Thyroid Diseases: 6 people, 7.69%
Hiv Infection: 6 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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