Mucinex and Ziac drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mucinex (guaifenesin) and Ziac (bisoprolol fumarate; hydrochlorothiazide). Common drug interactions include acute respiratory failure among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Mucinex and Ziac. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Mucinex?

Mucinex has active ingredients of guaifenesin. It is often used in cough. eHealthMe is studying from 29,749 Mucinex users. Check the latest studies of Mucinex.

What is Ziac?

Ziac has active ingredients of bisoprolol fumarate; hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 4,451 Ziac users. Check the latest studies of Ziac.

On Jul, 27, 2026

18 people who take Mucinex and Ziac together, and have interactions are studied.

What are the common drug interactions of Mucinex and Ziac, by gender? *:

female:

Acute respiratory failure
Chills (felling of cold)
Hypoxia (low oxygen in tissues)
Asthenia (weakness)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chronic kidney disease
Fatigue (feeling of tiredness)
Headache (pain in head)
Heart rate increased
Laceration (tearing of soft body tissue)

male:

Chronic kidney disease
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Embolic stroke (stroke due to obstruction due to an embolus)
Gait disturbance
Headache (pain in head)
Heart rate irregular
Hyperacusis (disorder in loudness perception)

What are the common drug interactions of Mucinex and Ziac, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Gait disturbance
Headache (pain in head)
Heart rate irregular
Hyperacusis (disorder in loudness perception)
Photophobia (extreme sensitivity to light)

50-59:

Chronic kidney disease
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Multiple injuries
Pain
Acute respiratory failure
Hypoxia (low oxygen in tissues)

60+:

Abdominal discomfort
Arterial stenosis (abnormal narrowing of the aortic valve in the heart)
Osteomyelitis (infection of bone)
Pyrexia (fever)
Rash
Retinal artery occlusion (blockage of retinal artery)
Sedation
Syncope (loss of consciousness with an inability to maintain postural tone)
Vision blurred
Vomiting

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 27.78%
Pain: 5 people, 27.78%
High Blood Cholesterol: 4 people, 22.22%
Hiv Infection: 3 people, 16.67%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 16.67%
Restless Leg Syndrome (a powerful urge to move your legs): 3 people, 16.67%
Hypokalemia (low potassium): 3 people, 16.67%
Fluid Retention (an abnormal accumulation of fluid in the blood): 3 people, 16.67%
Insomnia (sleeplessness): 3 people, 16.67%
Diabetes: 3 people, 16.67%

* Approximation only. Some reports may have incomplete information.

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