Mucomyst and Pepcid drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Mucomyst (acetylcysteine) and Pepcid (famotidine). Common drug interactions include anxiety among females and death among males.
The phase IV clinical study analyzes what interactions people have when they take Mucomyst and Pepcid. It is created by eHealthMe based on reports of 63 people who take the same drugs from the FDA, and is updated regularly.
What is Mucomyst?
Mucomyst has active ingredients of acetylcysteine. eHealthMe is studying from 1,835 Mucomyst users. Check the latest studies of Mucomyst.
What is Pepcid?
Pepcid has active ingredients of famotidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 55,774 Pepcid users. Check the latest studies of Pepcid.
63 people who take Mucomyst and Pepcid together, and have interactions are studied.

What are the common drug interactions of Mucomyst and Pepcid, by gender? *:
female:
- Anxiety
- Diarrhoea
- Fear
- Haematoma (collection of blood outside the blood vessels)
- Pyrexia (fever)
- Renal impairment (severely reduced kidney function)
- Renal injury (kidney injury)
- Septic shock (shock due to blood infection)
- Stress
- Acinetobacter infection (infection by group of bacteria commonly found in soil and water)
male:
- Death
- Renal failure (kidney dysfunction)
- Fear
- Hypertension (high blood pressure)
- Infection
- Injury
- Organ failure
- Pain
- Pneumonia
- Renal injury (kidney injury)
What are the common drug interactions of Mucomyst and Pepcid, by age (0-1 to 60+)? *:
0-1:
- Bronchiolitis (inflammation of the membranes lining the bronchioles in lungs)
- Dysphagia (a condition in which swallowing is difficult or painful)
- Increased bronchial secretion
- Respiratory failure (inadequate gas exchange by the respiratory system)
2-9:
- Hypertension (high blood pressure)
- Infection
- Acinetobacter infection (infection by group of bacteria commonly found in soil and water)
- Diarrhoea
- Diarrhoea haemorrhagic (bloody diarrhoea)
- Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
- Haematoma (collection of blood outside the blood vessels)
- Pleural effusion (water on the lungs)
- Pyrexia (fever)
- Septic shock (shock due to blood infection)
10-19:
n/a
20-29:
- Blood potassium decreased
- Disseminated intravascular coagulation (systemic activation of blood coagulation)
- Loin pain (pain originates from kidney)
- Nephritis (inflammation of the nephrons in the kidneys)
- Pyelonephritis (inflammation of kidney caused by bacteria)
- Pyrexia (fever)
- White blood cells urine positive
30-39:
n/a
40-49:
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Blood pressure decreased
- Haematoma (collection of blood outside the blood vessels)
- Heart rate increased
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
50-59:
- Cardiac disorder
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Death
- Depression
- Organ failure
- Emotional distress
- Stress
- Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
- Agitation (state of anxiety or nervous excitement)
- Anaemia (lack of blood)
60+:
- Pneumonia
- Renal failure (kidney dysfunction)
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Wound infection staphylococcal
- Acidosis (build-up of carbon dioxide in the blood)
- Acute respiratory failure
- Anaemia (lack of blood)
- Anxiety
- Blood creatinine increased
- Cardiac arrest
What are the existing conditions these people have? *
- Pain: 12 people, 19.05%
- Hypotension (abnormally low blood pressure): 10 people, 15.87%
- Nausea (feeling of having an urge to vomit): 8 people, 12.70%
- High Blood Pressure: 8 people, 12.70%
- Constipation: 8 people, 12.70%
- Insomnia (sleeplessness): 7 people, 11.11%
- Infection: 7 people, 11.11%
- Indigestion: 7 people, 11.11%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 9.52%
- Osteoporosis (bones weak and more likely to break): 5 people, 7.94%
* Approximation only. Some reports may have incomplete information.
Do you take Mucomyst and Pepcid?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Mucomyst and Pepcid:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Mucomyst:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Pepcid:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Mucomyst and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pepcid and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on acetylcysteine and famotidine (the active ingredients of Mucomyst and Pepcid, respectively), and Mucomyst and Pepcid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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