Multihance and Valcyte drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Multihance (gadobenate dimeglumine) and Valcyte (valganciclovir hydrochloride). Common drug interactions include arthralgia among females and nephrogenic systemic fibrosis among males.

The phase IV clinical study analyzes what interactions people have when they take Multihance and Valcyte. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Multihance?

Multihance has active ingredients of gadobenate dimeglumine. eHealthMe is studying from 5,786 Multihance users. Check the latest studies of Multihance.

What is Valcyte?

Valcyte has active ingredients of valganciclovir hydrochloride. It is often used in cmv - immunocompromised host. eHealthMe is studying from 6,409 Valcyte users. Check the latest studies of Valcyte.



On Jul, 15, 2026

34 people who take Multihance and Valcyte together, and have interactions are studied.

Multihance and Valcyte drug interactions.

What are the common drug interactions of Multihance and Valcyte, by gender? *:

female:

  1. Arthralgia (joint pain)
  2. Emotional distress
  3. Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
  4. General physical health deterioration (weak health status)
  5. Injury
  6. Mobility decreased (ability to move is reduced)
  7. Oedema (fluid collection in tissue)
  8. Rash erythematous (redness of the skin)
  9. Joint contracture (a permanent shortening of a muscle or joint)
  10. Pruritus (severe itching of the skin)

male:

  1. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  2. Mobility decreased (ability to move is reduced)
  3. Skin lesion
  4. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  5. General physical health deterioration (weak health status)
  6. Skin hypertrophy (skin cells enlarges)
  7. Skin induration (an abnormally hard spot or area on the skin)
  8. Extremity contracture (permanent shortening of a muscle or joint of arms and legs)
  9. Myalgia (muscle pain)
  10. Joint range of motion decreased (disease of joint movement)

What are the common drug interactions of Multihance and Valcyte, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Anxiety
  2. Arthralgia (joint pain)
  3. Burning sensation
  4. Dysstasia (difficulty in standing)
  5. Emotional distress
  6. Erythema (redness of the skin)
  7. Injury
  8. Joint range of motion decreased (disease of joint movement)
  9. Joint stiffness
  10. Limb discomfort (discomfort in leg)

30-39:

  1. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  2. Pain
  3. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  4. Anxiety
  5. General physical health deterioration (weak health status)
  6. Scar
  7. Mobility decreased (ability to move is reduced)
  8. Burning sensation
  9. Emotional distress
  10. Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)

40-49:

  1. Dry skin
  2. Dyspnoea (difficult or laboured respiration)
  3. Excoriation (to tear or wear off the skin of)
  4. Extremity contracture (permanent shortening of a muscle or joint of arms and legs)
  5. Granuloma (a small area of inflammation due to tissue injury)
  6. Hypoaesthesia (reduced sense of touch or sensation)
  7. Insomnia (sleeplessness)
  8. Lichenification (thickening and hardening of the skin)
  9. Lung disorder (lung disease)
  10. Muscle fibrosis (fibrous muscle)

50-59:

  1. Joint range of motion decreased (disease of joint movement)
  2. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  3. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  4. Pain
  5. Skin induration (an abnormally hard spot or area on the skin)
  6. Skin tightness
  7. Erythema (redness of the skin)
  8. Scar
  9. Skin hyperpigmentation (disorders affect the colour of your skin)
  10. Pruritus (severe itching of the skin)

60+:

  1. Breast fibrosis (the thickening and scarring of connective tissue, usually as a result of injury in breast)
  2. Exercise tolerance decreased
  3. Pain in extremity
  4. Peau d'orange (orange peel skin)
  5. Rash macular (small, flat red spots)
  6. Skin discolouration (change of skin colour)
  7. Skin fibrosis (fibrous tissue formation on skin)
  8. Skin hypertrophy (skin cells enlarges)
  9. Skin induration (an abnormally hard spot or area on the skin)
  10. Skin plaque (red, scaly patches to appear on the skin)

What are the existing conditions these people have? *

  1. Nuclear Magnetic Resonance Imaging Abdominal: 9 people, 26.47%
  2. Nuclear Magnetic Resonance Imaging Brain: 6 people, 17.65%
  3. Computerised Tomogram Abdomen: 5 people, 14.71%
  4. Bipolar Disorder (mood disorder): 3 people, 8.82%
  5. Anaemia (lack of blood): 3 people, 8.82%
  6. Pulmonary Hypertension (increase in blood pressure in the lung artery): 2 people, 5.88%
  7. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 5.88%
  8. Diabetes: 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Multihance and Valcyte?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Multihance and Valcyte:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Multihance:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Valcyte:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Multihance and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Valcyte and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on gadobenate dimeglumine and valganciclovir hydrochloride (the active ingredients of Multihance and Valcyte, respectively), and Multihance and Valcyte (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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