Mupirocin and Xarelto drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mupirocin (mupirocin) and Xarelto (rivaroxaban). Common drug interactions include myasthenia gravis among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Mupirocin and Xarelto. It is created by eHealthMe based on reports of 74 people who take the same drugs from the FDA, and is updated regularly.

What is Mupirocin?

Mupirocin has active ingredients of mupirocin. It is often used in impetigo. eHealthMe is studying from 5,940 Mupirocin users. Check the latest studies of Mupirocin.

What is Xarelto?

Xarelto has active ingredients of rivaroxaban. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 212,377 Xarelto users. Check the latest studies of Xarelto.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

74 people who take Mupirocin and Xarelto together, and have interactions are studied.

Mupirocin and Xarelto drug interactions.

What are the common drug interactions of Mupirocin and Xarelto, by gender? *:

female:

Myasthenia gravis (a chronic condition that causes muscles to tire and weaken easily)
Neutropenia (an abnormally low number of neutrophils)
Peripheral swelling
Pruritus (severe itching of the skin)
Sepsis (a severe blood infection that can lead to organ failure and death)
Skin cancer
Stomatitis (inflammation of mucous membrane of mouth)
Accident
Atrioventricular block first degree (heart block first degree)
Blood pressure increased

male:

Death
Dizziness
Basal ganglia infarction (disruption of the blood flow in the small blood vessels in the white matter of the cerebral cortex)
Bone density decreased
Brain stem microhaemorrhage (haemorrhage occurs in the brain stem)
Cellulitis (infection under the skin)
Cerebellar infarction (impaired blood circulation to cerebellum)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Decreased appetite
Diarrhoea

What are the common drug interactions of Mupirocin and Xarelto, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Pruritus (severe itching of the skin)
Skin disorder (skin disease)

20-29:

n/a

30-39:

n/a

40-49:

Asthma
Dyspnoea (difficult or laboured respiration)
Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
Erythema (redness of the skin)
Impaired gastric emptying
Malaise (a feeling of general discomfort or uneasiness)
Myasthenia gravis (a chronic condition that causes muscles to tire and weaken easily)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pain
Postural orthostatic tachycardia syndrome (abnormal increase in heart rate on becoming upright)

50-59:

Influenza
Infusion related reaction
Infusion site erythema (reddening of the skin at infusion site)
Infusion site rash
Infusion site urticaria (rash of round, red welts on the skin at infusion site)
Malaise (a feeling of general discomfort or uneasiness)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Post-traumatic stress disorder
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)

60+:

Dizziness
Nausea (feeling of having an urge to vomit)
Pruritus (severe itching of the skin)
Stomatitis (inflammation of mucous membrane of mouth)
Swelling
Urinary tract infection
Cardiac disorder
Abdominal distension
Accident
Asthenia (weakness)

What are the existing conditions these people have? *

High Blood Pressure: 9 people, 12.16%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 8 people, 10.81%
Diabetes: 6 people, 8.11%
Immune System Disorder: 5 people, 6.76%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 6.76%
Pain: 5 people, 6.76%
Type 2 Diabetes: 5 people, 6.76%
Insomnia (sleeplessness): 5 people, 6.76%
Itching: 5 people, 6.76%
Nausea (feeling of having an urge to vomit): 5 people, 6.76%

* Approximation only. Some reports may have incomplete information.

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