Mysoline and Oxycontin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mysoline (primidone) and Oxycontin (oxycodone hydrochloride). Common drug interactions include osteosclerosis among females and gait disturbance among males.

The phase IV clinical study analyzes what interactions people have when they take Mysoline and Oxycontin. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Mysoline?

Mysoline has active ingredients of primidone. It is often used in essential tremor. eHealthMe is studying from 2,849 Mysoline users. Check the latest studies of Mysoline.

What is Oxycontin?

Oxycontin has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 212,533 Oxycontin users. Check the latest studies of Oxycontin.

On Jul, 08, 2026

45 people who take Mysoline and Oxycontin together, and have interactions are studied.

Mysoline and Oxycontin drug interactions.

What are the common drug interactions of Mysoline and Oxycontin, by gender? *:

female:

Osteosclerosis (an elevation in bone density)
Pain in jaw
Decreased appetite
Inflammation
Asthenia (weakness)
Oedema peripheral (superficial swelling)
Constipation
Swelling face
Depression
Insomnia (sleeplessness)

male:

Gait disturbance
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Aortic dilatation
Arrhythmia (irregular heartbeat)
Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
Arteriovenous fistula site complication
Arthralgia (joint pain)
Atelectasis (partial or complete collapse of the lung)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bone disorder

What are the common drug interactions of Mysoline and Oxycontin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anxiety
Decreased appetite
Depression
Disturbance in attention
Hypoaesthesia (reduced sense of touch or sensation)
Memory impairment
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Oedema peripheral (superficial swelling)
Speech disorder
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

30-39:

n/a

40-49:

Drug addiction
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)

50-59:

Hypotension (abnormally low blood pressure)
Otitis media chronic (long lasting inflammation of the middle ear)
Abscess neck (neck abscesses)
Addison's disease (addison's disease, a hormonal disorder disease)
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Anaemia of chronic disease
Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
Atelectasis (partial or complete collapse of the lung)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bone disorder

60+:

Aortic arteriosclerosis (hardening of the aortic arteries)
Atelectasis (partial or complete collapse of the lung)
Pain in jaw
Confusional state
Constipation
Dyspnoea (difficult or laboured respiration)
Abdominal pain
Actinic keratosis (skin disease due to sun exposure)
Alveolar osteitis (complication of wound healing following extraction of a tooth)
Anxiety

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 12 people, 26.67%
Hypercalcaemia Of Malignancy (elevated calcium (ca+) level in the blood with cancer): 11 people, 24.44%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 6 people, 13.33%
Depression: 4 people, 8.89%
Tremor (trembling or shaking movements in one or more parts of your body): 3 people, 6.67%
Osteoporosis (bones weak and more likely to break): 3 people, 6.67%
High Blood Pressure: 3 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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