Mysoline and Solu-cortef drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mysoline (primidone) and Solu-cortef (hydrocortisone sodium succinate). Common drug interactions include cardiac arrest among females and abscess neck among males.

The phase IV clinical study analyzes what interactions people have when they take Mysoline and Solu-cortef. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Mysoline?

Mysoline has active ingredients of primidone. It is often used in essential tremor. eHealthMe is studying from 2,849 Mysoline users. Check the latest studies of Mysoline.

What is Solu-cortef?

Solu-cortef has active ingredients of hydrocortisone sodium succinate. eHealthMe is studying from 7,983 Solu-cortef users. Check the latest studies of Solu-cortef.

On Jul, 13, 2026

13 people who take Mysoline and Solu-cortef together, and have interactions are studied.

Mysoline and Solu-cortef drug interactions.

What are the common drug interactions of Mysoline and Solu-Cortef, by gender? *:

female:

Cardiac arrest
Cardiac disorder
Cardiac failure congestive
Cardiomegaly (increased size of heart than normal)
Cardiovascular disorder (heart diseases)
Cellulitis (infection under the skin)
Coagulopathy (blood's ability to clot is impaired)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Deafness
Decreased appetite

male:

Abscess neck (neck abscesses)
Addison's disease (addison's disease, a hormonal disorder disease)
Arthralgia (joint pain)
Atelectasis (partial or complete collapse of the lung)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bone disorder
Breast calcifications (deposits of calcium that can be seen on a mammogram of the breast)
Breast haematoma (blood-filled swelling in the breast)
Cardiac arrest
Cardiac disorder

What are the common drug interactions of Mysoline and Solu-Cortef, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Rash
Urticaria (rash of round, red welts on the skin that itch intensely)

50-59:

Cardiac arrest
Cardiac disorder
Cardiac failure congestive
Cardiomegaly (increased size of heart than normal)
Cardiovascular disorder (heart diseases)
Cellulitis (infection under the skin)
Coagulopathy (blood's ability to clot is impaired)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Deafness
Decreased appetite

60+:

Abscess neck (neck abscesses)
Addison's disease (addison's disease, a hormonal disorder disease)
Arthralgia (joint pain)
Atelectasis (partial or complete collapse of the lung)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bone disorder
Breast calcifications (deposits of calcium that can be seen on a mammogram of the breast)
Breast haematoma (blood-filled swelling in the breast)
Cardiac arrest
Cardiac disorder

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 11 people, 84.62%
Hypercalcaemia Of Malignancy (elevated calcium (ca+) level in the blood with cancer): 11 people, 84.62%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 6 people, 46.15%
High Blood Pressure: 1 person, 7.69%
High Blood Cholesterol: 1 person, 7.69%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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