Nac and Allegra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nac (n - acetyl cysteine) and Allegra (fexofenadine hydrochloride). Common drug interactions include arthralgia among females and tendon injury among males.

The phase IV clinical study analyzes what interactions people have when they take Nac and Allegra. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Nac?

Nac has active ingredients of n - acetyl cysteine. eHealthMe is studying from 855 Nac users. Check the latest studies of Nac.

What is Allegra?

Allegra has active ingredients of fexofenadine hydrochloride. It is often used in allergies. eHealthMe is studying from 75,497 Allegra users. Check the latest studies of Allegra.

On Jul, 08, 2026

26 people who take Nac and Allegra together, and have interactions are studied.

What are the common drug interactions of Nac and Allegra, by gender? *:

female:

Arthralgia (joint pain)
Device occlusion
Hereditary angioedema (recurrent episodes of severe swelling)
Infusion site extravasation (flow of (blood or lymph) from infusion site)
Migraine (headache)
Upper respiratory tract infection
Dizziness
Ear congestion
Hypotension (abnormally low blood pressure)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)

male:

Tendon injury

What are the common drug interactions of Nac and Allegra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Adverse event

20-29:

n/a

30-39:

Aphonia (inability to produce voice)
Decreased appetite
Depression
Dizziness
Dysphagia (a condition in which swallowing is difficult or painful)
Feeling of despair
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Larynx irritation
Sedation
Self-injurious ideation

40-49:

Fatigue (feeling of tiredness)
Arthralgia (joint pain)
Asthma
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Device occlusion
Dizziness
Ear congestion
Fall
Headache (pain in head)
Hereditary angioedema (recurrent episodes of severe swelling)

50-59:

Attention deficit/hyperactivity disorder
Chest discomfort
Cough
Headache (pain in head)
Lipase increased
Pancreatitis (inflammation of pancreas)
Throat irritation

60+:

Arthralgia (joint pain)
Back pain
Neck pain
Rash
Skin irritation
Spinal fracture (fracture in one of vertebrae)
Tendon injury
Urinary tract infection
Vulvovaginal candidiasis (vulvovaginal infection by fungi)
Vulvovaginal pain

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 11 people, 42.31%
Immune System Disorder: 6 people, 23.08%
B-Lymphocyte Abnormalities (abnormal population of b lymphocytes in the blood, bone marrow, or tissues): 6 people, 23.08%
Asthma: 5 people, 19.23%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 11.54%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 7.69%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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