Naltrexone hydrochloride and Morphine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Naltrexone hydrochloride (naltrexone hydrochloride) and Morphine (morphine sulfate). Common drug interactions include drug withdrawal syndrome among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Naltrexone hydrochloride and Morphine. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Naltrexone hydrochloride?

Naltrexone hydrochloride has active ingredients of naltrexone hydrochloride. It is often used in alcoholism. eHealthMe is studying from 1,712 Naltrexone hydrochloride users. Check the latest studies of Naltrexone hydrochloride.

What is Morphine?

Morphine has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 182,913 Morphine users. Check the latest studies of Morphine.

On Jul, 14, 2026

15 people who take Naltrexone hydrochloride and Morphine together, and have interactions are studied.

Naltrexone hydrochloride and Morphine drug interactions.

What are the common drug interactions of Naltrexone Hydrochloride and Morphine, by gender? *:

female:

Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
Death
Drug ineffective
Adverse event
Asthenia (weakness)
Dehydration (dryness resulting from the removal of water)
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Diarrhoea
Gait disturbance

male:

Anaemia (lack of blood)
Dehydration (dryness resulting from the removal of water)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Retching (strong involuntary effort to vomit)
Thrombocytopenia (decrease of platelets in blood)
Agitation (state of anxiety or nervous excitement)
Chills (felling of cold)
Confusional state
Diarrhoea
Hyperhidrosis (abnormally increased sweating)

What are the common drug interactions of Naltrexone Hydrochloride and Morphine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Cardiac arrest
Cardiomegaly (increased size of heart than normal)
Drug toxicity
Duodenitis (inflammation of the duodenum)
Gastritis erosive (a break in the surface layer of the membrane lining the stomach with infection)
Insomnia (sleeplessness)
Mania (a state of abnormally elevated or irritable mood)
Pulmonary congestion (congestion in the lungs)
Pulmonary oedema (fluid accumulation in the lungs)
Type 2 diabetes mellitus

30-39:

n/a

40-49:

Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Death
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
Agitation (state of anxiety or nervous excitement)
Chills (felling of cold)
Confusional state
Diarrhoea
Hyperhidrosis (abnormally increased sweating)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Retching (strong involuntary effort to vomit)

50-59:

Anaemia (lack of blood)
Dehydration (dryness resulting from the removal of water)
Thrombocytopenia (decrease of platelets in blood)
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Sensitisation (the state of being sensitive)

60+:

Drug ineffective
Adverse event
Tremor (trembling or shaking movements in one or more parts of your body)
Vomiting
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
Asthenia (weakness)
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Gait disturbance
Hypokalaemia (low potassium)

What are the existing conditions these people have? *

Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 26.67%
Back Pain: 3 people, 20.00%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 13.33%
Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 2 people, 13.33%
Drug Dependence: 2 people, 13.33%
Tumor Pain: 1 person, 6.67%
Thyroid Diseases: 1 person, 6.67%
Stress And Anxiety: 1 person, 6.67%
Sleep Disorder: 1 person, 6.67%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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