Naprelan and Folic acid drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Naprelan (naproxen sodium) and Folic acid (folic acid). Common drug interactions include sinusitis among females and atrial fibrillation among males.
The phase IV clinical study analyzes what interactions people have when they take Naprelan and Folic acid. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.
What is Naprelan?
Naprelan has active ingredients of naproxen sodium. eHealthMe is studying from 731 Naprelan users. Check the latest studies of Naprelan.
What is Folic acid?
Folic acid has active ingredients of folic acid. It is often used in rheumatoid arthritis. eHealthMe is studying from 165,025 Folic acid users. Check the latest studies of Folic acid.
14 people who take Naprelan and Folic acid together, and have interactions are studied.

What are the common drug interactions of Naprelan and Folic Acid, by gender? *:
female:
- Sinusitis (inflammation of sinus)
- Ankle fracture
- Arthralgia (joint pain)
- Brain injury
- Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
- Fall
- Hepatic enzyme increased
- Intervertebral disc protrusion (spinal disc protrusion)
- Nasopharyngitis (inflammation of the nasopharynx)
- Nerve injury
male:
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Coma (state of unconsciousness lasting more than six hours)
- Confusion
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
- Encephalitis (inflammation of the brain)
- Encephalopathy (functioning of the brain is affected by some agent or condition)
- Headache (pain in head)
- Hyperpyrexia (extremely high fever)
- Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
- Malaise (a feeling of general discomfort or uneasiness)
What are the common drug interactions of Naprelan and Folic Acid, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Hepatic enzyme increased
- Influenza
- Sinusitis (inflammation of sinus)
40-49:
- Feeling hot
- Hyperhidrosis (abnormally increased sweating)
- Muscle spasms (muscle contraction)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Anaemia (lack of blood)
- Arthralgia (joint pain)
- Ascites (accumulation of fluid in the abdominal cavity)
- Cough
- Dehydration (dryness resulting from the removal of water)
- Drug ineffective
50-59:
- Arthralgia (joint pain)
- Colitis (inflammation of colon)
- Malaise (a feeling of general discomfort or uneasiness)
- Nasopharyngitis (inflammation of the nasopharynx)
- Road traffic accident
- Sinusitis (inflammation of sinus)
- Urinary tract infection
60+:
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Coma (state of unconsciousness lasting more than six hours)
- Headache (pain in head)
- Hyperpyrexia (extremely high fever)
- Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
- Malaise (a feeling of general discomfort or uneasiness)
- Neck pain
- Ventricular arrhythmia (problem with the rate or rhythm of the heartbeat)
- Meningitis listeria (a bacterial infection of the membranes covering the brain and spinal cord (meninges))
- Pulmonary oedema (fluid accumulation in the lungs)
What are the existing conditions these people have? *
- Pain: 4 people, 28.57%
- Sleep Disorder: 2 people, 14.29%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 14.29%
- High Blood Cholesterol: 2 people, 14.29%
- Breakthrough Pain: 2 people, 14.29%
- Amyotrophic Lateral Sclerosis (nervous system disease that attacks nerve cells called neurons in your brain and spinal cord): 2 people, 14.29%
- Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 7.14%
- Joint Pain: 1 person, 7.14%
- Insomnia (sleeplessness): 1 person, 7.14%
- Inflammation: 1 person, 7.14%
* Approximation only. Some reports may have incomplete information.
Do you take Naprelan and Folic acid?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Naprelan (731 reports)
- Folic acid (165,025 reports)
Browse all drug interactions of Naprelan and Folic acid:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Naprelan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Folic acid:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Naprelan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Folic acid and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on naproxen sodium and folic acid (the active ingredients of Naprelan and Folic acid, respectively), and Naprelan and Folic acid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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