Naprosyn and Pulmozyme drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Naprosyn (naproxen) and Pulmozyme (dornase alfa). Common drug interactions include pneumonia among females and infective pulmonary exacerbation of cystic fibrosis among males.

The phase IV clinical study analyzes what interactions people have when they take Naprosyn and Pulmozyme. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Naprosyn?

Naprosyn has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 16,738 Naprosyn users. Check the latest studies of Naprosyn.

What is Pulmozyme?

Pulmozyme has active ingredients of dornase alfa. It is often used in cystic fibrosis. eHealthMe is studying from 20,012 Pulmozyme users. Check the latest studies of Pulmozyme.

On Jul, 14, 2026

15 people who take Naprosyn and Pulmozyme together, and have interactions are studied.

Naprosyn and Pulmozyme drug interactions.

What are the common drug interactions of Naprosyn and Pulmozyme, by gender? *:

female:

Pneumonia
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Administration site reaction
Infusion site vesicles (fluid- or air-filled cavity or sac at infusion site)
Lung infection

male:

Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Productive cough
Chorioretinopathy (collection of fluid under the retina that results in visual distortion)
Compartment syndrome (painful condition that occurs when pressure within the muscles builds to dangerous levels)
Myositis (inflammation of the muscles)
Pulmonary haemorrhage (acute bleeding from the lung)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Somnolence (a state of near-sleep, a strong desire for sleep)
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Stress

What are the common drug interactions of Naprosyn and Pulmozyme, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Blood glucose increased
Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Lung infection
Acute sinusitis

20-29:

Bacterial infection
Compartment syndrome (painful condition that occurs when pressure within the muscles builds to dangerous levels)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Myositis (inflammation of the muscles)
Pneumonia
Pulmonary haemorrhage (acute bleeding from the lung)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)

30-39:

Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)

40-49:

n/a

50-59:

Productive cough

60+:

n/a

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 26.67%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 13.33%
Rickets (softening of bones): 1 person, 6.67%
Osteopenia (a condition where bone mineral density is lower than normal): 1 person, 6.67%
Itching: 1 person, 6.67%
Infective Exacerbation Of Bronchiectasis (severe infective lung disease): 1 person, 6.67%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 1 person, 6.67%
Cough: 1 person, 6.67%
Constipation: 1 person, 6.67%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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