Naprosyn and Zebeta drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Naprosyn (naproxen) and Zebeta (bisoprolol fumarate). Common drug interactions include abdominal discomfort among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Naprosyn and Zebeta. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Naprosyn?

Naprosyn has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 16,738 Naprosyn users. Check the latest studies of Naprosyn.

What is Zebeta?

Zebeta has active ingredients of bisoprolol fumarate. It is often used in high blood pressure. eHealthMe is studying from 1,734 Zebeta users. Check the latest studies of Zebeta.

On Jul, 14, 2026

16 people who take Naprosyn and Zebeta together, and have interactions are studied.

What are the common drug interactions of Naprosyn and Zebeta, by gender? *:

female:

Abdominal discomfort
Acute myocardial infarction (acute heart attack)
Arthropathy
Death
Fatigue (feeling of tiredness)
Haemorrhage (bleeding)
Haemorrhoidal haemorrhage (bleeding from the haemorrhoids)
Heart rate increased
Hyperuricaemia (level of uric acid in the blood that is abnormally high)
Nausea (feeling of having an urge to vomit)

male:

Chronic kidney disease
Renal impairment (severely reduced kidney function)
Renal injury (kidney injury)
Alcoholism (problems with alcohol)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)

What are the common drug interactions of Naprosyn and Zebeta, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Chronic kidney disease
Drug ineffective
Nephrogenic anaemia (anaemia due to kidney disease)
Polyp
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Somnolence (a state of near-sleep, a strong desire for sleep)
Spinal osteoarthritis (joint cartilage loss in spine)
Upper respiratory tract infection

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 56.25%
Renal Disorder (kidney disease): 8 people, 50.00%
Gout (uric acid crystals building up in the body): 8 people, 50.00%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 18.75%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 12.50%
Prostatic Disorder: 2 people, 12.50%
Joint Pain: 2 people, 12.50%
Multiple Myeloma (cancer of the plasma cells): 1 person, 6.25%
Infection: 1 person, 6.25%
Inflammation: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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