Methimazole and Levaquin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Methimazole (methimazole) and Levaquin (levofloxacin). Common drug interactions include osteoporosis among females and cardiac disorder among males.
The phase IV clinical study analyzes what interactions people have when they take Methimazole and Levaquin. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.
What is Methimazole?
Methimazole has active ingredients of methimazole. It is often used in hyperthyroidism. eHealthMe is studying from 8,016 Methimazole users. Check the latest studies of Methimazole.
What is Levaquin?
Levaquin has active ingredients of levofloxacin. It is often used in sinusitis. eHealthMe is studying from 56,638 Levaquin users. Check the latest studies of Levaquin.
41 people who take Methimazole and Levaquin together, and have interactions are studied.

What are the common drug interactions of Methimazole and Levaquin, by gender? *:
female:
- Osteoporosis (bones weak and more likely to break)
- Otitis externa (external ear infection)
- Otorrhoea (discharge from the ear)
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Periodontitis (inflammation of the tissue around the teeth)
- Primary sequestrum (piece of dead bone that has become separated during the process of necrosis from normal/sound bone)
- Purulent discharge (discharge that contains pus)
- Pyrexia (fever)
- Resorption bone increased
- Respiratory tract infection
male:
- Cardiac disorder
- Lower respiratory tract infection
- Back pain
- Cardiac murmur (an heart sound in valve abnormality)
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
- Cardioactive drug level above therapeutic
- Cardioactive drug level below therapeutic
- Diarrhoea
- Diastolic dysfunction
- Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
What are the common drug interactions of Methimazole and Levaquin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Chronic kidney disease
- Nephrogenic anaemia (anaemia due to kidney disease)
- Renal failure (kidney dysfunction)
- Renal injury (kidney injury)
40-49:
- Anxiety
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Actinomycosis (infection that causes sores, or abscesses)
- Adenoma benign (non-cancerous tumour -secreting)
- Alopecia (absence of hair from areas of the body)
- Anaemia (lack of blood)
- Atelectasis (partial or complete collapse of the lung)
- Bone disorder
- Bone formation increased
50-59:
- Fatigue (feeling of tiredness)
- Heart injury
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
- Malignant melanoma (skin cancer rises from melancytes)
- Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Pain in extremity
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Pulmonary embolism (blockage of the main artery of the lung)
- Renal tubular necrosis (death of kidney tubules)
60+:
- Adverse event
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Dyspnoea (difficult or laboured respiration)
- Kidney infection
- Obstruction
- Respiratory tract infection
- Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
- Upper respiratory tract infection
- Abasia (inability to walk)
- Platelet count decreased
What are the existing conditions these people have? *
- Stress And Anxiety: 7 people, 17.07%
- High Blood Pressure: 5 people, 12.20%
- Immunodeficiency Common Variable: 5 people, 12.20%
- Urinary Tract Infection: 4 people, 9.76%
- Premenstrual Syndrome: 4 people, 9.76%
- Pain: 4 people, 9.76%
- Depression: 4 people, 9.76%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 9.76%
- High Blood Cholesterol: 4 people, 9.76%
- Chronic Thyroiditis (long lasting inflammation of thyroid gland): 3 people, 7.32%
* Approximation only. Some reports may have incomplete information.
Do you take Methimazole and Levaquin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Methimazole (8,016 reports)
- Levaquin (56,638 reports)
Browse all drug interactions of Methimazole and Levaquin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Methimazole:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Levaquin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Methimazole and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Levaquin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Bhuvan KC, ALrasheedy AA, Ibrahim MI, "A case report from Nepalese community pharmacy on levofloxacin induced severe abdominal pain", Saudi Pharmaceutical Journal, 2013 Jul .
- MITTAL V, ARCHANA D, GUPTA A, SRIVASTAV U, CHANDRA V, SAXENA A, AGRAWAL P, "Aphasia: a Rarest Complication with a Well Known Drug Levofloxacin", Medical Science, 2013 Jan .
- Bhuvan KC, ALrasheedy AA, Ibrahim MI, "A case report from Nepalese community pharmacy on levofloxacin induced severe abdominal pain", Saudi Pharmaceutical Journal, 2013 Jul .
- MITTAL V, ARCHANA D, GUPTA A, SRIVASTAV U, CHANDRA V, SAXENA A, AGRAWAL P, "Aphasia: a Rarest Complication with a Well Known Drug Levofloxacin", Medical Science, 2013 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on methimazole and levofloxacin (the active ingredients of Methimazole and Levaquin, respectively), and Methimazole and Levaquin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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