Narcan and Gralise drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Narcan (naloxone hydrochloride) and Gralise (gabapentin). Common drug interactions include fall among females and foreign body sensation in eyes among males.

The phase IV clinical study analyzes what interactions people have when they take Narcan and Gralise. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Narcan?

Narcan has active ingredients of naloxone hydrochloride. eHealthMe is studying from 3,687 Narcan users. Check the latest studies of Narcan.

What is Gralise?

Gralise has active ingredients of gabapentin. It is often used in neuralgia. eHealthMe is studying from 4,282 Gralise users. Check the latest studies of Gralise.

On Jul, 26, 2026

15 people who take Narcan and Gralise together, and have interactions are studied.

What are the common drug interactions of Narcan and Gralise, by gender? *:

female:

Fall
Nausea (feeling of having an urge to vomit)
Pyrexia (fever)
Retching (strong involuntary effort to vomit)
Vomiting
Ankle fracture
Aphasia (damage to the parts of the brain that control language)
Brain injury
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Decreased appetite

male:

Foreign body sensation in eyes (feeling of something in eye)

What are the common drug interactions of Narcan and Gralise, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Fall
Pain
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Weight decreased
Blindness transient (sudden loss of vision)
Screaming (a long loud piercing cry)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Arthropathy
Nausea (feeling of having an urge to vomit)
Retching (strong involuntary effort to vomit)

60+:

Ankle fracture
Brain injury
Somnolence (a state of near-sleep, a strong desire for sleep)
Surgical failure
Foreign body sensation in eyes (feeling of something in eye)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Fall
Intervertebral disc protrusion (spinal disc protrusion)
Nerve injury
Pneumonia

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 8 people, 53.33%
Depression: 8 people, 53.33%
Procedural Pain: 8 people, 53.33%
Post Herpetic Neuralgia (neuralgia caused by the varicella zoster virus): 8 people, 53.33%
Pain: 8 people, 53.33%
Stress And Anxiety: 7 people, 46.67%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 33.33%
Nervous System Disorder (a general class of medical conditions affecting the nervous system): 4 people, 26.67%
Quit Smoking: 4 people, 26.67%
Neurological Symptom (symptoms of nervous system disease): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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