Neupogen and Aricept drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Neupogen (filgrastim) and Aricept (donepezil hydrochloride). Common drug interactions include haemoglobin decreased among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Neupogen and Aricept. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Neupogen?

Neupogen has active ingredients of filgrastim. It is often used in agranulocytosis. eHealthMe is studying from 23,898 Neupogen users. Check the latest studies of Neupogen.

What is Aricept?

Aricept has active ingredients of donepezil hydrochloride. It is often used in alzheimer's disease. eHealthMe is studying from 24,756 Aricept users. Check the latest studies of Aricept.



On Jul, 11, 2026

14 people who take Neupogen and Aricept together, and have interactions are studied.

Neupogen and Aricept drug interactions.

What are the common drug interactions of Neupogen and Aricept, by gender? *:

female:

  1. Haemoglobin decreased
  2. Platelet count decreased
  3. Abdominal pain
  4. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  5. Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
  6. Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
  7. Oedema peripheral (superficial swelling)
  8. Psychotic disorder
  9. Septic shock (shock due to blood infection)
  10. Weight increased

male:

  1. Death
  2. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  3. Bone pain
  4. Decreased appetite
  5. Diarrhoea haemorrhagic (bloody diarrhoea)
  6. Dizziness
  7. Dyspnoea (difficult or laboured respiration)
  8. Epigastric discomfort
  9. Faeces discoloured
  10. Fatigue (feeling of tiredness)

What are the common drug interactions of Neupogen and Aricept, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Anxiety
  2. Base excess increased
  3. Blood bilirubin increased
  4. Blood chloride increased
  5. Blood glucose increased
  6. Blood osmolarity increased
  7. Blood ph increased
  8. Blood potassium decreased
  9. Blood pressure increased
  10. Blood sodium increased

40-49:

  1. Breast cancer metastatic
  2. Haemoglobin decreased
  3. Malignant neoplasm progression (cancer tumour came back)
  4. Metastases to bone marrow (cancer spreads to bone marrow)

50-59:

n/a

60+:

  1. Haemoglobin decreased
  2. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  3. Weight increased
  4. White blood cell count decreased
  5. Abdominal discomfort
  6. Abdominal distension
  7. Abdominal pain upper
  8. Angiopathy (generic term for a disease of the blood vessels)
  9. Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
  10. Asthenia (weakness)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 3 people, 21.43%
  2. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 14.29%
  3. Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 2 people, 14.29%
  4. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 1 person, 7.14%
  5. Malignant Lymphoid Neoplasm (malignant growth or tumour caused by abnormal and uncontrolled cell division in lymph node): 1 person, 7.14%
  6. Leukopenia (less number of white blood cells in blood): 1 person, 7.14%
  7. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 7.14%
  8. Breast Cancer Metastatic: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Neupogen and Aricept?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Neupogen and Aricept:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Neupogen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Aricept:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Neupogen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Aricept and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on filgrastim and donepezil hydrochloride (the active ingredients of Neupogen and Aricept, respectively), and Neupogen and Aricept (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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