Neupogen and Bumetanide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Neupogen (filgrastim) and Bumetanide (bumetanide). Common drug interactions include dizziness postural among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Neupogen and Bumetanide. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Neupogen?

Neupogen has active ingredients of filgrastim. It is often used in agranulocytosis. eHealthMe is studying from 23,898 Neupogen users. Check the latest studies of Neupogen.

What is Bumetanide?

Bumetanide has active ingredients of bumetanide. It is often used in fluid retention. eHealthMe is studying from 20,532 Bumetanide users. Check the latest studies of Bumetanide.



On Jul, 16, 2026

30 people who take Neupogen and Bumetanide together, and have interactions are studied.

Neupogen and Bumetanide drug interactions.

What are the common drug interactions of Neupogen and Bumetanide, by gender? *:

female:

  1. Dizziness postural
  2. Abdominal pain
  3. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  4. Methicillin-resistant staphylococcal aureus infection
  5. Oedema peripheral (superficial swelling)
  6. Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
  7. Acute respiratory distress syndrome
  8. Adult respiratory distress syndrome (type of lung (pulmonary) failure)
  9. Bacterial test positive
  10. Blood bicarbonate increased

male:

  1. Death
  2. Thrombocytopenia (decrease of platelets in blood)
  3. Acute graft versus host disease in liver (acute complication in liver following an allogeneic tissue/blood transplant)
  4. Aspergillosis (an infection caused by a fungus called aspergillus)
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  6. Cardiac asthma (wheezing, coughing or shortness of breath due to congestive heart failure)
  7. Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
  8. Chronic kidney disease
  9. Death unexplained
  10. Decreased appetite

What are the common drug interactions of Neupogen and Bumetanide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Methicillin-resistant staphylococcal aureus infection
  2. Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
  3. Acute respiratory distress syndrome
  4. Adult respiratory distress syndrome (type of lung (pulmonary) failure)
  5. Lower respiratory tract infection
  6. Lung consolidation (a condition whereby the lung tissues solidify because of the accumulation of solid and liquid material in the air spaces)
  7. Respiratory disorder (respiratory disease)
  8. Respiratory tract infection
  9. Vital capacity decreased

20-29:

n/a

30-39:

n/a

40-49:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Renal impairment (severely reduced kidney function)
  4. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

50-59:

  1. Blood creatinine increased
  2. Acute graft versus host disease in liver (acute complication in liver following an allogeneic tissue/blood transplant)
  3. Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
  4. Difficulty in walking
  5. Fungal infection
  6. Haematuria (presence of blood in urine)
  7. Haematuria present (presence of blood in urine due to trauma)
  8. Hepatotoxicity (chemical-driven liver damage)
  9. Oedema lower limb (fluid collection in tissue of lower leg)
  10. Renal failure acute (rapid kidney dysfunction)

60+:

  1. Dizziness postural
  2. Death
  3. Rash
  4. Respiratory tract infection
  5. Aspergillosis (an infection caused by a fungus called aspergillus)
  6. Bacterial test positive
  7. Blood bicarbonate increased
  8. Blood calcium decreased
  9. Blood chloride decreased
  10. Blood glucose increased

What are the existing conditions these people have? *

  1. Pulmonary Hypertension Secondary (increase in blood pressure in the lung artery): 4 people, 13.33%
  2. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 4 people, 13.33%
  3. Asthma: 4 people, 13.33%
  4. Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 3 people, 10.00%
  5. Abdominal Pain Upper: 3 people, 10.00%
  6. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 6.67%
  7. Multiple Myeloma (cancer of the plasma cells): 2 people, 6.67%
  8. Idiopathic Pulmonary Fibrosis (chronic lung disease): 2 people, 6.67%
  9. High Blood Pressure: 2 people, 6.67%
  10. High Blood Cholesterol: 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Neupogen and Bumetanide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Neupogen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Bumetanide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Neupogen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bumetanide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on filgrastim and bumetanide (the active ingredients of Neupogen and Bumetanide, respectively), and Neupogen and Bumetanide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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