Neupro and Hydroxyzine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Neupro (rotigotine) and Hydroxyzine (hydroxyzine hydrochloride). Common drug interactions include abnormal dreams among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Neupro and Hydroxyzine. It is created by eHealthMe based on reports of 58 people who take the same drugs from the FDA, and is updated regularly.

What is Neupro?

Neupro has active ingredients of rotigotine. It is often used in parkinson's disease. eHealthMe is studying from 11,393 Neupro users. Check the latest studies of Neupro.

What is Hydroxyzine?

Hydroxyzine has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 54,069 Hydroxyzine users. Check the latest studies of Hydroxyzine.

On Jul, 19, 2026

58 people who take Neupro and Hydroxyzine together, and have interactions are studied.

Neupro and Hydroxyzine drug interactions.

What are the common drug interactions of Neupro and Hydroxyzine, by gender? *:

female:

Abnormal dreams
Anaemia (lack of blood)
Blood pressure increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cataract (clouding of the lens inside the eye)
Cervical vertebral fracture
Chest pain
Confusional state
Contusion (a type of hematoma of tissue in which capillaries)
Cough

male:

Death
Angioedema (rapid swelling of the dermis)
Eyelid ptosis (falling of the upper or lower eyelid)
Gait disturbance
Heart rate decreased
Hypertension (high blood pressure)
Jaw disorder (jaw disease)
Lethargy (tiredness)
Lip oedema (swelling of lip)
Migraine (headache)

What are the common drug interactions of Neupro and Hydroxyzine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Device occlusion
Abdominal pain
Gastric infection (infection of stomach)
Pain
Pain in extremity

40-49:

Muscle spasms (muscle contraction)
Serum ferritin decreased
Diarrhoea
Diarrhoea haemorrhagic (bloody diarrhoea)
Flatulence (flatus expelled through the anus)
Palpitations (feelings or sensations that your heart is pounding or racing)
Peripheral swelling
Vomiting
Blood glucose increased
Blood triglycerides increased

50-59:

Pain
Alcohol abuse
Alcohol withdrawal syndrome
Alcoholism (problems with alcohol)
Attention deficit hyperactivity disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness)
Back pain
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Compulsive shopping
Depression
Drug abuse

60+:

Saliva discolouration (change in colour of saliva)
Sputum discoloured
Feeling hot
Infrequent bowel movements
Pallor
Angioedema (rapid swelling of the dermis)
Back pain
Cardiac disorder
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Dysarthria (speech disorder)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 27 people, 46.55%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 24 people, 41.38%
On And Off Phenomenon: 5 people, 8.62%
Restless Leg Syndrome (a powerful urge to move your legs): 4 people, 6.90%
Urticaria (rash of round, red welts on the skin that itch intensely): 3 people, 5.17%
Hallucinations (sensations that appear real but are created by your mind): 3 people, 5.17%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 5.17%
Delusion (a false belief or opinion): 3 people, 5.17%

* Approximation only. Some reports may have incomplete information.

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