Neupro and Premarin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Neupro (rotigotine) and Premarin (estrogens, conjugated). Common drug interactions include urinary tract infection among females and abdominal discomfort among males.

The phase IV clinical study analyzes what interactions people have when they take Neupro and Premarin. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Neupro?

Neupro has active ingredients of rotigotine. It is often used in parkinson's disease. eHealthMe is studying from 11,393 Neupro users. Check the latest studies of Neupro.

What is Premarin?

Premarin has active ingredients of estrogens, conjugated. It is often used in hormone replacement therapy. eHealthMe is studying from 99,630 Premarin users. Check the latest studies of Premarin.

On Jul, 13, 2026

27 people who take Neupro and Premarin together, and have interactions are studied.

What are the common drug interactions of Neupro and Premarin, by gender? *:

female:

Urinary tract infection
Headache (pain in head)
Lacrimation increased
Rhinorrhoea (watery mucus discharge from the nose)
Sneezing
Drug ineffective
Emotional distress
Malaise (a feeling of general discomfort or uneasiness)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety

male:

Abdominal discomfort
Anxiety
Compulsive sexual behaviour (unable to manage his/her sexual behaviour)
Confusional state
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hallucination, visual (seeing things that aren't there)
Lethargy (tiredness)
Postoperative wound infection
Psoriasis (immune-mediated disease that affects the skin)
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)

What are the common drug interactions of Neupro and Premarin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Psoriasis (immune-mediated disease that affects the skin)
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)

60+:

Dyspepsia (indigestion)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Confusional state
Diarrhoea
Dysarthria (speech disorder)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hallucination, visual (seeing things that aren't there)
Heart rate increased
Hypertension (high blood pressure)
Lethargy (tiredness)

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 6 people, 22.22%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 11.11%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 11.11%
Restless Leg Syndrome (a powerful urge to move your legs): 2 people, 7.41%
Hiv Infection: 2 people, 7.41%
Hallucinations (sensations that appear real but are created by your mind): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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