Neurontin and Embeda drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Neurontin (gabapentin) and Embeda (morphine sulfate; naltrexone hydrochloride). Common drug interactions include sinusitis among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Neurontin and Embeda. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.

What is Neurontin?

Neurontin has active ingredients of gabapentin. It is often used in neuralgia. eHealthMe is studying from 107,468 Neurontin users. Check the latest studies of Neurontin.

What is Embeda?

Embeda has active ingredients of morphine sulfate; naltrexone hydrochloride. eHealthMe is studying from 1,407 Embeda users. Check the latest studies of Embeda.

On Jul, 10, 2026

46 people who take Neurontin and Embeda together, and have interactions are studied.

What are the common drug interactions of Neurontin and Embeda, by gender? *:

female:

Sinusitis (inflammation of sinus)
Upper respiratory tract infection
Weight decreased
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
Drug hypersensitivity
Fall
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Somnambulism (sleep walking)
Dyskinesia (abnormality or impairment of voluntary movement)

male:

Nausea (feeling of having an urge to vomit)
Arthralgia (joint pain)
Pain in extremity
Adverse drug reaction
Agitation (state of anxiety or nervous excitement)
Anger
Completed suicide (act of taking one's own life)
Mood swings (an extreme or rapid change in mood)
Pruritus (severe itching of the skin)
Rash

What are the common drug interactions of Neurontin and Embeda, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Adverse drug reaction
Completed suicide (act of taking one's own life)
Dyspnoea (difficult or laboured respiration)
Hypotension (abnormally low blood pressure)

30-39:

Migraine (headache)
Fatigue (feeling of tiredness)
Influenza like illness
Pyrexia (fever)

40-49:

Drug ineffective
Proctalgia (pain in the rectum)
Drug effect decreased
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Abdominal pain
Arthropathy
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Diarrhoea
Fatigue (feeling of tiredness)

50-59:

Nausea (feeling of having an urge to vomit)
Arthralgia (joint pain)
Chills (felling of cold)
Decreased appetite
Fatigue (feeling of tiredness)
Feeling cold
Feeling hot
Hyperhidrosis (abnormally increased sweating)
Hypersomnia (excessive daytime sleepiness (eds))
Lethargy (tiredness)

60+:

Drug hypersensitivity
Dyskinesia (abnormality or impairment of voluntary movement)
Headache (pain in head)
Malaise (a feeling of general discomfort or uneasiness)
Personality change
Post-traumatic stress disorder
Sepsis (a severe blood infection that can lead to organ failure and death)
Social avoidant behaviour (avoiding social connection a personality disorder)
Somnambulism (sleep walking)
Visual impairment

What are the existing conditions these people have? *

Pain: 10 people, 21.74%
Neuropathy Peripheral (surface nerve damage): 9 people, 19.57%
High Blood Pressure: 9 people, 19.57%
Back Pain: 8 people, 17.39%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 15.22%
Stress And Anxiety: 6 people, 13.04%
Immunodeficiency Common Variable: 6 people, 13.04%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 13.04%
High Blood Cholesterol: 5 people, 10.87%
Indigestion: 4 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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