Neurontin and Epitol drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Neurontin (gabapentin) and Epitol (carbamazepine). Common drug interactions include acute coronary syndrome among females and urticaria among males.
The phase IV clinical study analyzes what interactions people have when they take Neurontin and Epitol. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Neurontin?
Neurontin has active ingredients of gabapentin. It is often used in neuralgia. eHealthMe is studying from 107,468 Neurontin users. Check the latest studies of Neurontin.
What is Epitol?
Epitol has active ingredients of carbamazepine. It is often used in bipolar disorder. eHealthMe is studying from 397 Epitol users. Check the latest studies of Epitol.
12 people who take Neurontin and Epitol together, and have interactions are studied.

What are the common drug interactions of Neurontin and Epitol, by gender? *:
female:
- Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
- Acute left ventricular failure (heart attack)
- Acute respiratory failure
- Chronic kidney disease
- Drug effect decreased
- Application site perspiration (production of fluids secreted by the sweat glands in the skin of mammals at application site)
- Drug effect increased
- Drug ineffective
- Lung neoplasm malignant (cancer tumour of lung)
- Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
male:
- Urticaria (rash of round, red welts on the skin that itch intensely)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Burning sensation
- Cardiac failure congestive
- Cardiovascular disorder (heart diseases)
- Chest discomfort
- Chest pain
- Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
- Cough
- Depression
What are the common drug interactions of Neurontin and Epitol, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Dyspnoea (difficult or laboured respiration)
- Pruritus (severe itching of the skin)
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Anaphylactic reaction (serious allergic reaction)
- Arthralgia (joint pain)
- Back pain
- Balance disorder
- Blindness transient (sudden loss of vision)
- Burning sensation
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
50-59:
- Drug effect decreased
- Lung neoplasm malignant (cancer tumour of lung)
- Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
- Therapeutic response unexpected
60+:
- Cardiac failure congestive
- Cardiovascular disorder (heart diseases)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Ischaemia (insufficient supply of blood to an organ, usually due to a blocked artery)
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
What are the existing conditions these people have? *
- High Blood Cholesterol: 6 people, 50.00%
- Pain: 6 people, 50.00%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 33.33%
- High Blood Pressure: 3 people, 25.00%
- Migraine (headache): 3 people, 25.00%
- Nausea (feeling of having an urge to vomit): 3 people, 25.00%
- Fabry's Disease (build up of a particular type of fat, called globotriaosylceramide, in the body's cells): 3 people, 25.00%
- Skin Disorder (skin disease): 2 people, 16.67%
- Heart Attack: 2 people, 16.67%
- Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 16.67%
* Approximation only. Some reports may have incomplete information.
Do you take Neurontin and Epitol?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Neurontin and Epitol:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Neurontin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Epitol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Neurontin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Epitol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
- Puvanendran R, Teo HZ, "Case report of use of Black Cohosh for carbamazepine induced hot flushes in a post menopausal woman", Maturitas, 2017 Jun .
- Scarff JR, "The Potential for Somnambulism Associated with Gabapentin", The Internet Journal of Psychiatry, 2014 Jan .
- Arshad F, Ladakhi Y, Khan MA, "A rare case of carbamazepine induced pancreatitis", International Journal of Students’ Research, 2013 Jul .
- Yava?o?lu I, Sarg?n G, Demirbulat A, "Carbamazepine and hematological malignancies", Turkish journal of haematology: official journal of Turkish Society of Haematology, 2013 Jan .
- de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
- Puvanendran R, Teo HZ, "Case report of use of Black Cohosh for carbamazepine induced hot flushes in a post menopausal woman", Maturitas, 2017 Jun .
- Scarff JR, "The Potential for Somnambulism Associated with Gabapentin", The Internet Journal of Psychiatry, 2014 Jan .
- Arshad F, Ladakhi Y, Khan MA, "A rare case of carbamazepine induced pancreatitis", International Journal of Students’ Research, 2013 Jul .
- Yava?o?lu I, Sarg?n G, Demirbulat A, "Carbamazepine and hematological malignancies", Turkish journal of haematology: official journal of Turkish Society of Haematology, 2013 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on gabapentin and carbamazepine (the active ingredients of Neurontin and Epitol, respectively), and Neurontin and Epitol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
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