Neurontin and Hycodan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Neurontin (gabapentin) and Hycodan (homatropine methylbromide; hydrocodone bitartrate). Common drug interactions include lung disorder among females and upper respiratory tract infection among males.

The phase IV clinical study analyzes what interactions people have when they take Neurontin and Hycodan. It is created by eHealthMe based on reports of 76 people who take the same drugs from the FDA, and is updated regularly.

What is Neurontin?

Neurontin has active ingredients of gabapentin. It is often used in neuralgia. eHealthMe is studying from 107,468 Neurontin users. Check the latest studies of Neurontin.

What is Hycodan?

Hycodan has active ingredients of homatropine methylbromide; hydrocodone bitartrate. It is often used in cough. eHealthMe is studying from 769 Hycodan users. Check the latest studies of Hycodan.

On Jul, 12, 2026

76 people who take Neurontin and Hycodan together, and have interactions are studied.

Neurontin and Hycodan drug interactions.

What are the common drug interactions of Neurontin and Hycodan, by gender? *:

female:

Lung disorder (lung disease)
Anaemia (lack of blood)
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Asthenia (weakness)
Dehydration (dryness resulting from the removal of water)
Fatigue (feeling of tiredness)
Hodgkin's disease (cancer originating from white blood cells)
Impetigo (contagious skin infection)
Keratoconjunctivitis sicca (inflammation of the conjunctiva and cornea of the eye with decreased tears)

male:

Upper respiratory tract infection
Anxiety
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Bradycardia (abnormally slow heart action)
Candidiasis (candidiasis or thrush is a fungal infection)
Carotid artery disease
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Dyspnoea (difficult or laboured respiration)
Ear disorder

What are the common drug interactions of Neurontin and Hycodan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Hodgkin's disease (cancer originating from white blood cells)
Impetigo (contagious skin infection)
Keratoconjunctivitis sicca (inflammation of the conjunctiva and cornea of the eye with decreased tears)
Lacrimation increased
Lung disorder (lung disease)
Lymphadenopathy (disease or enlargement of lymph nodes)
Neuropathy peripheral (surface nerve damage)
Oral herpes (viral infection of mouth)
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands)

30-39:

Arthralgia (joint pain)
Csf neutrophil count increased
Csf white blood cell count increased
Dizziness
Drug effect decreased
Fatigue (feeling of tiredness)
Headache (pain in head)
Hemiparesis (weakness on one side of the body)
Hypoaesthesia (reduced sense of touch or sensation)
Insomnia (sleeplessness)

40-49:

Anaemia (lack of blood)
Hypokalaemia (low potassium)
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Nausea (feeling of having an urge to vomit)
Non-small cell lung cancer metastatic (type of epithelial lung cancer spreads to other parts)

50-59:

Upper respiratory tract infection
Aggression
Constipation
Delirium (wild excitement)
Drug dependence
Drug toxicity
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Dysarthria (speech disorder)
Emotional distress
Flat affect (absence of emotional response to a situation)

60+:

Dyspnoea (difficult or laboured respiration)
Renal failure acute (rapid kidney dysfunction)
Candidiasis (candidiasis or thrush is a fungal infection)
Carotid artery disease
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Dizziness
Ear disorder
Flushing (the warm, red condition of human skin)
Groin pain
Intervertebral disc displacement

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 26 people, 34.21%
Depression: 20 people, 26.32%
Pain: 19 people, 25.00%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 19 people, 25.00%
Sleep Disorder: 17 people, 22.37%
Muscle Spasms (muscle contraction): 16 people, 21.05%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 16 people, 21.05%
Renal Cell Carcinoma Stage Unspecified (kidney cancer in unknown stage): 8 people, 10.53%
Oropharyngeal Pain: 6 people, 7.89%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 6 people, 7.89%

* Approximation only. Some reports may have incomplete information.

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