Nexium and Atr drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nexium (esomeprazole magnesium) and Atr (atractylodes). Common drug interactions include hypoglycaemia among females and gastrointestinal perforation among males.

The phase IV clinical study analyzes what interactions people have when they take Nexium and Atr. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Nexium?

Nexium has active ingredients of esomeprazole magnesium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 245,677 Nexium users. Check the latest studies of Nexium.

What is Atr?

Atr has active ingredients of atractylodes. eHealthMe is studying from 103 Atr users. Check the latest studies of Atr.



On Jul, 11, 2026

13 people who take Nexium and Atr together, and have interactions are studied.

Nexium and Atr drug interactions.

What are the common drug interactions of Nexium and Atr, by gender? *:

female:

  1. Hypoglycaemia (deficiency of glucose in the bloodstream)
  2. Malaise (a feeling of general discomfort or uneasiness)
  3. Aortitis (inflammation of the aortic wall)
  4. Extrasystoles
  5. Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
  6. Atrial tachycardia (rhythm disturbance that arises in the atria)
  7. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  8. Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
  9. Atrioventricular block complete (heart block complete)
  10. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

male:

  1. Gastrointestinal perforation (hole in the digestive tract)
  2. Pneumonia
  3. Sepsis (a severe blood infection that can lead to organ failure and death)

What are the common drug interactions of Nexium and Atr, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Nausea (feeling of having an urge to vomit)
  2. Headache (pain in head)
  3. Chest pain
  4. Palpitations (feelings or sensations that your heart is pounding or racing)
  5. Cardiac failure
  6. Dizziness
  7. Hypoglycaemia (deficiency of glucose in the bloodstream)
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Extrasystoles
  10. Atrial tachycardia (rhythm disturbance that arises in the atria)

40-49:

  1. Arteritis (inflammation of the walls of arteries)
  2. Aortitis (inflammation of the aortic wall)
  3. Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)

50-59:

n/a

60+:

  1. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  2. Atrioventricular block complete (heart block complete)
  3. Platelet count decreased
  4. Pneumonia
  5. Pruritus (severe itching of the skin)
  6. Radial nerve palsy (paralysis of radial nerve)
  7. Sepsis (a severe blood infection that can lead to organ failure and death)
  8. Spinal compression fracture (fracture due to spinal compression on bone)
  9. Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
  10. Vertigo

What are the existing conditions these people have? *

  1. Hyperuricaemia (level of uric acid in the blood that is abnormally high): 7 people, 53.85%
  2. Gastritis - Chronic (long lasting inflammation of stomach): 7 people, 53.85%
  3. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 6 people, 46.15%
  4. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 6 people, 46.15%
  5. Bronchitis Chronic (inflammation of the mucous membrane in the bronchial tubes- chronic): 6 people, 46.15%
  6. Diabetes: 6 people, 46.15%
  7. Hypokalemia (low potassium): 6 people, 46.15%
  8. High Blood Pressure: 2 people, 15.38%
  9. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 15.38%
  10. Glomerulonephritis Membranous (nephritis with inflammation of the capillary loops in the renal glomeruli): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Nexium and Atr?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Nexium and Atr:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nexium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Atr:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nexium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Atr and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on esomeprazole magnesium and atractylodes (the active ingredients of Nexium and Atr, respectively), and Nexium and Atr (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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