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Nexium and Clomid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nexium (esomeprazole magnesium) and Clomid (clomiphene citrate). Common drug interactions include chronic kidney disease among females and depression among males.

The phase IV clinical study analyzes what interactions people have when they take Nexium and Clomid. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Nexium?

Nexium has active ingredients of esomeprazole magnesium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 245,677 Nexium users. Check the latest studies of Nexium.

What is Clomid?

Clomid has active ingredients of clomiphene citrate. It is often used in infertility female. eHealthMe is studying from 1,350 Clomid users. Check the latest studies of Clomid.

On Jul, 09, 2026

20 people who take Nexium and Clomid together, and have interactions are studied.

Nexium and Clomid drug interactions.

What are the common drug interactions of Nexium and Clomid, by gender? *:

female:

  1. Chronic kidney disease
  2. Live birth
  3. Gestational diabetes (diabetes in pregnancy)
  4. Maternal exposure during pregnancy (use of substance during pregnancy)
  5. Pregnancy
  6. Hyperkalaemia (damage to or disease of the kidney)
  7. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  8. Nephrogenic anaemia (anaemia due to kidney disease)
  9. Oedema (fluid collection in tissue)
  10. Renal failure (kidney dysfunction)

male:

  1. Depression
  2. Emotional distress
  3. Aortic valve incompetence
  4. Aphagia (inability or refusal to swallow)
  5. Apnoea (suspension of external breathing)
  6. Attention deficit/hyperactivity disorder
  7. Autism (a mental condition, present from early childhood, characterized by difficulty in communicating and forming relationships with other people and in using language and abstract concepts)
  8. Bradycardia (abnormally slow heart action)
  9. Cellulitis (infection under the skin)
  10. Drug ineffective

What are the common drug interactions of Nexium and Clomid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Anaemia (lack of blood)
  2. Cephalo-pelvic disproportion (situation in which baby head of body is too large to deliver)
  3. Drug ineffective
  4. Erectile dysfunction
  5. Sexual dysfunction (difficulty experienced by an individual or a couple during any stage of a normal sexual activity)

30-39:

  1. Chronic kidney disease
  2. Abortion spontaneous (naturally occurring miscarriage)
  3. Asthma
  4. Maternal exposure during pregnancy (use of substance during pregnancy)

40-49:

  1. Chronic kidney disease
  2. Hyperkalaemia (damage to or disease of the kidney)
  3. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  4. Nephrogenic anaemia (anaemia due to kidney disease)
  5. Oedema (fluid collection in tissue)
  6. Renal failure (kidney dysfunction)
  7. Renal tubular necrosis (death of kidney tubules)
  8. Live birth
  9. Maternal exposure during pregnancy (use of substance during pregnancy)
  10. Vanishing twin syndrome (twin/multiple fetuses disappears in the uterus during pregnancy)

50-59:

  1. Cellulitis (infection under the skin)
  2. Heart rate increased
  3. Hypertension (high blood pressure)
  4. Phlebitis (inflammation of the walls of a vein)
  5. Pulmonary embolism (blockage of the main artery of the lung)
  6. Pulmonary thrombosis (scarring in the lungs)

60+:

  1. Pain
  2. Cholecystitis chronic (long lasting infection of gallbladder)
  3. Osteomyelitis (infection of bone)
  4. Osteonecrosis of jaw (death of bone of jaw)
  5. Toothache (tooth pain)
  6. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  7. Dental caries
  8. Fatigue (feeling of tiredness)
  9. Gingival infection (gum infection)
  10. Haemorrhage (bleeding)

What are the existing conditions these people have? *

  1. Headache (pain in head): 7 people, 35.00%
  2. Joint Pain: 7 people, 35.00%
  3. High Blood Pressure: 6 people, 30.00%
  4. Depression: 6 people, 30.00%
  5. High Blood Cholesterol: 6 people, 30.00%
  6. Restless Leg Syndrome (a powerful urge to move your legs): 4 people, 20.00%
  7. Blood Pressure Abnormal: 4 people, 20.00%
  8. Plantar Fasciitis (painful inflammatory process of the plantar fascia): 4 people, 20.00%
  9. Diabetes: 4 people, 20.00%
  10. Hypersensitivity: 4 people, 20.00%

* Approximation only. Some reports may have incomplete information.

Do you take Nexium and Clomid?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Nexium and Clomid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nexium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Clomid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nexium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Clomid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on esomeprazole magnesium and clomiphene citrate (the active ingredients of Nexium and Clomid, respectively), and Nexium and Clomid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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